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Anti-Burnet Phage Antibody (IgG) by Immunoassay

Published: August 9, 2026Updated: August 15, 2026

This test measures the level of antibodies against the Burnet phage in your blood, which may help identify certain immune responses or infections.

Quick summary

["This test helps assess immune system activity related to specific viral exposures or autoimmune conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 15, 2026Editorial policy

Key facts at a glance

LOINC
44814-2
Short code
COX2IGM
Synonyms
C burnet Ph2 IgM Titr Ser IF
Category
chemistry
Sample
serum
Container
Serum separator tube (SST, gold-top) or red-top tube (no anticoagulant)
Units
N/A
Ref low
0
Ref high
1
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
Immunofluorescence assay (IFA) for detection of IgM antibodies against Coxiella burnetii phase 2 antigen
CPT
86638
SNOMED
31361000119108
Specimen volume
1.0 mL serum (minimum 0.5 mL)
Stability
Stable at room temperature (20–25°C) for 8 hours; refrigerated (2–8°C) for 7 days; frozen (-20°C or below) for up to 30 days. Avoid repeated freeze-thaw cycles.
Hemolysis max
100
Lipemia max
200
Icterus max
40
TAT
24–96 hours
Order
routine

What Is This Test Measuring?

The Burnet phage is a bacteriophage (a virus that infects bacteria) used in research to study immune responses. This test detects IgG antibodies produced in response to exposure to this phage, which can be part of a broader immune reaction to pathogens or experimental stimuli.

Why Might You Need This Test?

Testing for anti-Burnet phage antibodies is often done in research or specialized clinical settings to evaluate immune responses, particularly in studies involving vaccines, autoimmune conditions, or immune-related diseases. It may also be used in certain diagnostic contexts where phage-based assays are employed.

How Is the Sample Collected?

A blood sample is drawn from a vein, usually in your arm, by a healthcare professional. The blood is then processed to separate the serum or plasma for testing.

What Does the Result Mean?

Results are qualitative (positive or negative) and indicate the presence or absence of antibodies against the Burnet phage. A positive result suggests an immune response has occurred, while a negative result means no detectable antibodies were found.

Reference range

Titer <1:16 (Negative): No detectable IgM antibodies to phase 2 antigen. Titer ≥1:16 (Positive): Indicates recent or acute infection with Coxiella burnetii (Q fever). Titer 1:16–1:256 (Indeterminate/Low positive): Suggest repeat testing in 2–4 weeks. Titer ≥1:200 (Strong positive): Consistent with acute Q fever infection.N/A

Specimen: serum

No fasting or special preparation required. Patients should inform their healthcare provider of any recent vaccinations, current infections, or immunosuppressive therapy, as these may affect antibody response. Acute and convalescent serum samples (2–4 weeks apart) are recommended for accurate serologic diagnosis.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Anti-Burnet Phage Antibody (IgG)

Frequently asked questions

What Are Common Causes of Abnormal Results?
Anti-Burnet phage antibodies are not commonly evaluated in routine clinical practice. They may be relevant in research settings or specific diagnostic scenarios involving phage-based diagnostics. Abnormal results could indicate an immune response to experimental exposure or certain autoimmune conditions, but further clinical correlation is needed.
How Often Should This Test Be Done?
This test is rarely performed in standard medical practice. It may be ordered as part of a specialized study or research protocol. Follow your healthcare provider’s instructions for frequency and timing.
What Should I Do If My Results Are Abnormal?
If your test results are abnormal, discuss them with your healthcare provider. They will help interpret the results in the context of your health history and determine if further testing or treatment is needed.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy