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Chemokine (CC motif) ligand 11, Serum or Plasma

Published: August 9, 2026Updated: August 15, 2026

This test measures the level of a protein called chemokine CCL11, which plays a role in attracting certain white blood cells to areas of inflammation or infection in your body.

Quick summary

["CCL11 helps identify possible immune responses or allergic reactions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 15, 2026Editorial policy

Key facts at a glance

LOINC
98108-4
Short code
CCL11
Synonyms
CCL11 SerPl-mCnc
Category
chemistry
Sample
serum
Container
Serum separator tube (SST) or red-top tube for serum; plasma may be collected in EDTA or heparin tubes
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–99 years
Method
Immunoassay (e.g., ELISA or multiplex bead-based assay)
CPT
83520
SNOMED
121900001
Specimen volume
1-2 mL of serum or plasma
Stability
Serum/plasma stable for 24 hours at room temperature, 7 days at 2-8°C, and up to 3 months at -20°C or colder for long-term storage
Hemolysis max
2
Lipemia max
2
Icterus max
2
TAT
48–168 hours
Order
routine

What Does CCL11 Measure?

CCL11 is a small protein (chemokine) that signals immune cells to move toward sites of inflammation, allergies, or tissue damage. Elevated levels may suggest conditions involving chronic inflammation, allergic reactions, or certain immune disorders. This test is often used in research or specialized clinical settings to assess immune responses.

Why Might You Need This Test?

Your healthcare provider may order CCL11 testing if you have symptoms or conditions linked to immune cell recruitment, such as allergic reactions, certain cancers, or chronic inflammatory diseases. It may also be used in research or advanced diagnostic scenarios.

Sample Collection and Preparation

A blood sample is drawn from a vein in your arm. The blood is then separated into serum or plasma (the liquid part without or with clotting factors) for testing. This sample is sent to a lab for analysis using specialized techniques to measure CCL11 levels.

What Does a Result Mean?

Interpreting CCL11 results involves comparing your level to what is typically found in healthy individuals. While reference ranges can vary by lab, higher-than-normal levels may indicate increased immune activity, while lower levels might suggest reduced signaling in immune responses.

Reference range

Reference ranges vary by assay platform and laboratory; consult the performing laboratory's reference interval for accurate interpretation.N/A

Specimen: serum

No special patient preparation required. Specimen may be collected at any time of day as fasting is not required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

CCL11 (Eotaxin-1)

Frequently asked questions

What are the normal values for CCL11?
Normal values can vary by lab and testing method. Your healthcare provider will discuss your specific results in the context of your symptoms and medical history.
Could CCL11 levels change with diet or lifestyle?
Diet or lifestyle factors may indirectly influence immune responses, but CCL11 itself is not typically affected by diet. However, chronic conditions or medications affecting inflammation could influence results.
Is CCL11 testing covered by insurance?
Coverage depends on your insurance plan and clinical indication. Check with your insurance provider or healthcare provider to confirm if this test is covered under your specific circumstances.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy