Serum Chemokine (C-C Motif) Ligand 2 (CCL20) Measurement
This test measures the level of CCL20, a protein involved in immune system signaling, found in your blood serum. It may be used to assess immune responses or inflammation.
["CCL20 helps your immune system communicate and respond to infections or inflammation."]
Key facts at a glance
- LOINC
- 98112-6
- Short code
- CCL20
- Synonyms
- CCL20 SerPl-mCnc
- Category
- chemistry
- Sample
- serum
- Container
- Serum separator tube (SST) or red-top tube for serum; plasma may be collected in EDTA or heparin tubes
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- Immunoassay (e.g., ELISA, Luminex multiplex bead-based assay)
- CPT
- 83520 (Immunoassay for analyte other than infectious agent antibody or infectious agent antigen; quantitative, not otherwise specified)
- Specimen volume
- 1-2 mL of serum or plasma
- Stability
- Serum/plasma stable for 24 hours at room temperature, 7 days at 2-8°C, or up to 6 months at -20°C or below. Avoid repeated freeze-thaw cycles.
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 48–168 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if they suspect an immune-related condition, such as certain infections, autoimmune disorders, or responses to treatments like chemotherapy. It could also be part of a broader evaluation for conditions affecting inflammation or immune cell movement.
What to Expect Before the Test
No special preparation is typically needed. You may fast if instructed by your provider, but this test does not require fasting. Bring any medications or supplements you’re currently taking to your appointment.
What Happens During the Test
A healthcare professional will draw blood from a vein in your arm. The blood sample will be sent to a lab for analysis. The test measures CCL20 levels in your serum using a sensitive detection method.
What the Results Mean
Results are interpreted by your healthcare provider based on your overall health, symptoms, and medical history. Elevated levels may indicate an active immune response or inflammation, while lower levels might suggest reduced signaling in certain immune pathways.
Reference range
Reference values vary by assay platform and laboratory; consult the performing laboratory's reference range. Generally reported in pg/mL.N/A
No special preparation required. Fasting is not necessary.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
CCL20 Serum
Frequently asked questions
What could cause abnormal results?
How often should this test be repeated?
Does this test interact with medications?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy