Chemokine (C-C motif) ligand 2, mass concentration
This test measures the amount of CCL2, a protein involved in immune system signaling, in your blood. It helps assess inflammation or immune responses.
["CCL2 levels may indicate inflammation or immune activity in your body."]
Key facts at a glance
- LOINC
- 97105-1
- Short code
- CCL2-U
- Synonyms
- CCL2 Ur IA-mCnc
- Category
- chemistry
- Sample
- urine
- Container
- Sterile, leak-proof urine collection container
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- Immunoassay (e.g., ELISA, chemiluminescent immunoassay)
- Specimen volume
- 5-10 mL of urine
- Stability
- Stable for 24 hours at 2-8°C; for longer storage, freeze at -20°C or below. Avoid repeated freeze-thaw cycles.
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 24–168 hours
- Order
- routine
Why Is This Test Done?
Your healthcare provider may order this test to evaluate conditions linked to chronic inflammation, such as certain autoimmune diseases, infections, or organ damage. It can also be used in research or specialized clinical settings to monitor immune responses.
What Does a High or Low Level Mean?
Elevated CCL2 levels may suggest ongoing inflammation, immune activation, or conditions like rheumatoid arthritis, lupus, or infections. Lower-than-expected levels might raise questions about immune function but are less commonly interpreted alone.
Sample Collection and Preparation
A blood sample is typically drawn from a vein in your arm. The sample is processed to separate serum or plasma for testing. This test does not require fasting.
What to Expect Before the Test
No special preparation is needed, but inform your provider if you’re taking medications that could affect blood tests or have any allergies to blood collection supplies.
Reference range
Reference values vary by assay platform and laboratory; generally established locally per populationN/A
No special patient preparation required. Patient should follow normal hydration unless otherwise instructed by physician.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
CCL2 is a key signaling protein that recruits immune cells to sites of inflammation. High levels are often associated with chronic inflammatory diseases, cancer metastasis, or tissue damage. It can also be used in research to study immune responses or as a biomarker in clinical trials.
Short name
C-C Motif Chemokine 2 (CCL2) Level
Frequently asked questions
What causes changes in CCL2 levels?
How long does it take to get results?
Can lifestyle changes affect CCL2 levels?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy