Serum/plasma mass concentration of Chemokine (C-C motif) ligand 5
This test measures the amount of CCL5, a protein involved in immune response and inflammation, found in your blood.
["CCL5 helps your body fight infections and may be checked if you have symptoms of immune issues or inflammation."]
Key facts at a glance
- LOINC
- 98113-4
- Short code
- CCL5
- Synonyms
- CCL5 SerPl-mCnc
- Category
- chemistry
- Sample
- serum
- Container
- Serum separator tube (SST) or plasma tube with appropriate anticoagulant (EDTA or heparin) depending on assay requirements
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- ≥ 18 years
- Method
- Enzyme-Linked Immunosorbent Assay (ELISA) or multiplex bead-based immunoassay (Luminex)
- CPT
- 83520 (Immunoassay for analyte other than infectious agent antibody or infectious agent antigen; quantitative, not otherwise specified)
- SNOMED
- 39579001 (Chemokine CCL5 measurement)
- Specimen volume
- 1.0-2.0 mL of serum or plasma; minimum 0.5 mL required for analysis
- Stability
- Serum/plasma stable for 4 hours at room temperature (20-25°C), 24 hours refrigerated at 2-8°C, and up to 6 months frozen at -20°C or below. Avoid repeated freeze-thaw cycles.
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 48–168 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms like chronic fatigue, frequent infections, or unexplained swelling. It could also be part of an evaluation for autoimmune conditions or certain cancers.
What to Expect Before the Test
No special preparation is usually needed. You may fast for 8–12 hours before the test if instructed, but this is not always required. Bring any medications you’re currently taking to your appointment.
How the Test Works
A blood sample is drawn from a vein, typically in your arm. The sample is sent to a lab where it is analyzed to measure CCL5 levels using a sensitive immunoassay method.
What the Results Mean
Results are reported as mass concentration (in nanograms per milliliter or similar units). Higher than expected levels may suggest immune activation, while lower levels could indicate immune suppression or other conditions.
Reference range
Reference ranges vary by laboratory and assay methodology; typically established per individual laboratory's validation studies. Consult the performing laboratory's reference range documentation.N/A
No special patient preparation is required. However, patients should be advised that acute inflammatory conditions, infections, or recent vaccination may transiently elevate CCL5 levels.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
CCL5 (Serum/Plasma)
Frequently asked questions
What Does Elevated CCL5 Mean?
What Does Low CCL5 Mean?
How Often Should I Get This Test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy