C-D11a Cell Subtype Count in Fluid (e.g., Lymph Node or Tissue Aspirate)
This test measures the number of cells expressing the CD11a protein in a fluid sample, often obtained from lymph nodes or tissue biopsies. CD11a is a marker found on certain immune cells, including lymphocytes and some monocytes.
["CD11a+ cells help identify immune cell populations involved in inflammation or immune responses."]
Key facts at a glance
- LOINC
- 57393-1
- Short code
- CD11a
- Synonyms
- CD11a Cells NFr Fld
- Category
- chemistry
- Sample
- serum
- Container
- Sterile collection container for body fluid; EDTA or heparin anticoagulant tubes may be used for whole blood analysis; specific containers depend on body fluid type (e.g., sterile tube for synovial, CSF, BAL fluid)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- Flow cytometry using fluorescently labeled monoclonal antibodies directed against CD11a (LFA-1 alpha chain, ITGAL)
- CPT
- 86356
- SNOMED
- 395124003
- Specimen volume
- Minimum 1-2 mL of body fluid; volume requirements vary by specimen type and laboratory protocol. For peripheral blood flow cytometry, 3-5 mL of whole blood in EDTA tube is typically sufficient.
- Stability
- Specimen should be processed within 4-6 hours of collection for optimal cell viability and antigen expression. If delay is anticipated, specimens may be refrigerated at 2-8°C for up to 24 hours, though viability may decrease. Body fluid specimens should be transported at room temperature and processed promptly.
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 24–72 hours
- Order
- routine
What Is CD11a Used For?
CD11a is primarily used in medical settings to assess immune cell populations in samples like lymph node aspirates or tissue biopsies. It may aid in diagnosing conditions affecting immune function, such as certain lymphomas, infections, or inflammatory diseases.
How Is This Test Performed?
A small sample of fluid (e.g., from a lymph node biopsy) is collected and analyzed using flow cytometry or a similar technique. The test identifies and counts cells expressing the CD11a protein, which helps classify immune cell types.
Sample Collection and Preparation
Your healthcare provider will take a sample during a biopsy or aspiration procedure. The fluid is then processed in the lab to prepare it for testing, ensuring only the relevant cells are counted.
When Might You Need This Test?
This test may be recommended if you have symptoms like persistent lymph node swelling, unexplained fatigue, or suspected immune-related conditions. Doctors often use it alongside other tests to guide diagnosis.
Reference range
Reference ranges for CD11a expression vary by laboratory and specimen type. Results are typically reported as percentage of CD11a-positive cells and/or mean fluorescence intensity (MFI). Consult laboratory-specific reference ranges for interpretation.N/A
No special patient preparation required. Fasting is not necessary. Patients should inform their healthcare provider of any recent infections, immunosuppressive therapy, or vaccinations as these may affect immune cell populations.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Elevated or altered counts of CD11a+ cells can indicate immune system abnormalities, such as chronic inflammation, certain cancers (e.g., lymphomas), or immune deficiencies. Low or abnormal levels may suggest immune suppression or specific disorders affecting lymphocyte function.
Short name
CD11a+ Cell Count
Frequently asked questions
Why Was I Asked to Provide a Sample?
How Long Does It Take to Get Results?
Can I Influence the Results?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy