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Absolute count of CD11c+ cells within white blood cells (WBCs)

Published: August 9, 2026Updated: August 16, 2026

This test measures the number of white blood cells that express the CD11c protein, which is often associated with certain immune cell types. It may be used to assess immune function or identify specific blood cell abnormalities.

Quick summary

["This test helps evaluate immune cell populations in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
34634-6
Short code
CD1118LE
Synonyms
CD11+CD18+ Cells # WBC
Category
chemistry
Sample
serum
Container
EDTA (purple-top) vacutainer tube for flow cytometry; heparinized tube may be acceptable for some assays. ACD-A tubes are an acceptable alternative for immunophenotyping.
Units
N/A
Ref low
90
Ref high
100
Critical range
2 N/A – 30 N/A
Fasting
false
Population
adult
Sex
all
Age range
≥ 0 years
Method
Flow cytometry using fluorescently labeled monoclonal antibodies against CD11 and CD18 surface markers on leukocytes, with absolute cell counting via bead-based or volumetric methods.
CPT
86356
SNOMED
36414009
Specimen volume
Minimum 1 mL whole blood for adults; 0.5-1 mL for pediatric patients. For cord blood or neonatal testing, minimum 0.5 mL EDTA whole blood.
Stability
Specimen should be processed within 24-48 hours of collection when stored at room temperature (18-25°C). Do not refrigerate for flow cytometry applications, as cold-induced loss of CD18 surface expression may occur. Specimens should be analyzed as soon as possible; ideally within 24 hours.
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
24–72 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if they suspect an immune disorder, infection, or other conditions affecting white blood cells. It could also be part of a broader blood evaluation, such as a complete blood count (CBC), to look for unusual immune cell activity.

What to Expect During the Test

A simple blood draw is typically used to collect the sample. You may feel a slight pinch, but it usually takes only a few minutes. No special preparation is needed unless instructed by your doctor.

Sample Collection and Processing

Blood is drawn from a vein, usually in your arm, and sent to the lab for analysis. The CD11c+ cells are identified and counted using advanced laboratory techniques, often involving flow cytometry or similar methods.

What the Results Mean

Results are usually reported as an absolute count of CD11c+ cells per microliter of blood. While reference ranges can vary by lab, abnormal counts may indicate conditions like chronic inflammation, certain infections, or immune system disorders.

Reference range

Reference ranges vary by laboratory; CD11+CD18+ cells typically constitute 90-100% of granulocytes, monocytes, and macrophages, and 30-50% of lymphocytes. Reference ranges expressed as absolute count [#/volume] are laboratory-specific and should be interpreted alongside the percentage of leukocytes expressing CD11b/CD18 integrins.N/A

Specimen: serum

No special patient preparation required. Recent transfusions, immunosuppressive therapy, or corticosteroid use may affect leukocyte subset counts and should be noted on the requisition. For pediatric patients, parental/guardian consent is required for specimen collection.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

CD11c+ WBC Cell Count

Frequently asked questions

This test can help identify immune cell populations that may be elevated or reduced, which can be useful in diagnosing conditions such as certain leukemias, infections, or autoimmune diseases. It may also assist in monitoring treatment responses in patients with chronic immune-related conditions.
This test is not typically performed as a standalone screening test for most conditions. It is usually ordered in conjunction with other tests or clinical evaluations to provide a clearer picture of your health.
The CD11c protein is found on certain immune cells, such as dendritic cells and some lymphocytes. Abnormal counts may suggest an underlying immune dysfunction or response to infection.
If you have questions about your specific results, discuss them with your healthcare provider. They can help interpret the results in the context of your overall health and medical history.
No special preparation is required, but inform your healthcare provider about any medications or conditions that might affect blood test results.
This test may take several days to receive results, depending on lab processing times. Follow-up appointments may be scheduled if additional testing or evaluation is needed.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy