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CD14-Positive Blasts, Number Fraction in Bone Marrow

Published: August 9, 2026Updated: August 17, 2026

Measures the proportion of bone marrow blasts that carry the CD14 marker, which can help classify and monitor certain forms of leukemia.

Quick summary

["This test helps determine whether abnormal immature blood cells in the marrow express CD14."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
51075-0
Short code
CD14 Blasts/Blasts NFr Mar
Synonyms
CD14 Blasts/Blasts NFr Mar
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This test measures the fraction of blasts, or immature blood cells, in bone marrow that have the CD14 protein on their surface. CD14 is commonly associated with certain monocytic blood cells and is evaluated as part of leukemia testing.

Why might I need this test?

A clinician may order this test to investigate an unexplained increase in immature blood cells, classify a suspected leukemia, or monitor leukemia response to treatment. It is interpreted together with other laboratory and flow-cytometry findings.

How is the test performed?

A small bone marrow sample is collected and examined in the laboratory, usually by flow cytometry, to identify and count cells carrying CD14. The result is reported as the proportion of blasts that are CD14-positive.

How do I prepare for the test?

No special preparation is usually required for the laboratory measurement, but bone marrow collection is invasive. Follow your clinician's instructions and ask about local anesthesia, bleeding risk, and activity restrictions after the procedure.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

CD14-positive blasts in bone marrow

Frequently asked questions

What does a CD14-positive blast mean?
It is an immature blood cell in the bone marrow that carries the CD14 surface marker. CD14 is often found on monocytic cells, but the marker alone does not identify a specific disease.
Is this the same as a complete blood count?
No. A complete blood count measures cells in circulating blood, while this test examines the makeup of blasts in bone marrow.
Does bone marrow testing require hospitalization?
Not always. The procedure is often performed in an outpatient setting with local anesthesia, but your clinician will explain the setting and any observation period based on your health and the collection method.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy