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CD14-Positive Blasts, Bone Marrow — Amount Concentration

Published: August 9, 2026Updated: August 17, 2026

Measures the concentration of CD14-positive blast cells in bone marrow fluid, usually as part of evaluating suspected leukemia or another marrow disorder.

Quick summary

["This test identifies and measures immature marrow cells that carry the CD14 marker to help evaluate possible blood cancers."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
51077-6
Short code
CD14 Blasts Mar-aCnc
Synonyms
CD14 Blasts Mar-aCnc
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

Blasts are immature blood-forming cells. CD14 is a marker found on certain white blood cells, especially cells of the monocyte/macrophage lineage. This test measures the amount of CD14-positive blasts in a bone marrow fluid sample.

Why might I need this test?

A clinician may order this test when examining the bone marrow for signs of leukemia, lymphoma, myelodysplastic syndrome, or another blood-forming disorder. It can help characterize abnormal immature cells and support diagnosis, classification, and treatment planning.

How is the test performed?

A small sample of bone marrow fluid is usually collected by bone marrow aspiration. Laboratory personnel examine the fluid using methods such as flow cytometry to identify and count cells carrying CD14. The report may provide the result as cells per unit volume of marrow fluid.

How do I prepare for the test?

Bone marrow aspiration is performed only when your clinician determines that it is needed. Follow the clinic's instructions about medications, bleeding risk, and local anesthesia or sedation. Fasting is generally not required unless your care team specifically directs you to fast.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

CD14+ blasts in bone marrow

Frequently asked questions

What does a CD14-positive blast mean?
It is an immature blood-forming cell that displays the CD14 marker. CD14 is commonly associated with the monocyte/macrophage family, but this finding alone does not establish a specific diagnosis.
Is this the same as a routine blood test?
No. This test examines bone marrow fluid rather than circulating blood, so it generally requires a bone marrow aspiration performed by a clinician.
Will an abnormal result definitely mean I have leukemia?
No. An abnormal blast result may raise concern for a blood disorder, but diagnosis requires review of the blood, marrow cell structure, flow cytometry findings, and sometimes additional tests by your healthcare team.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy