CD14 Cells in Whole Blood (Absolute Count)
This test measures the number of CD14-positive cells in your blood. CD14 cells are a type of white blood cell involved in immune responses, often linked to inflammation or infection.
["CD14 cells help your body fight infections and respond to inflammation."]
Key facts at a glance
- LOINC
- 27011-6
- Short code
- CD14
- Synonyms
- CD14 Cells # Bld
- Category
- chemistry
- Sample
- whole-blood
- Container
- EDTA (lavender-top) tube, preferably EDTA K2 or K3; alternatively ACD (yellow-top) tube for flow cytometry immunophenotyping
- Units
- N/A
- Ref low
- 170
- Ref high
- 1100
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- Flow cytometry using fluorescently labeled monoclonal antibodies against CD14 surface marker, with enumeration by absolute counting beads or dual-platform methodology
- CPT
- 86356
- SNOMED
- 118761001
- Specimen volume
- Minimum 3-5 mL of whole blood; for pediatric patients, minimum 1-2 mL
- Stability
- Specimen should be processed within 24-48 hours of collection when stored at room temperature (18-25°C). Do not refrigerate or freeze. Optimal analysis within 24 hours for best viability and antigen preservation.
- Hemolysis max
- 100
- Lipemia max
- 500
- Icterus max
- 50
- TAT
- 4–24 hours
- Order
- routine
What Is CD14 Used For?
CD14 cells are part of the immune system and play a role in detecting pathogens like bacteria. They also help regulate inflammation. This test may be used to assess immune function, monitor infections, or evaluate conditions affecting white blood cells, such as certain cancers or autoimmune diseases.
When Might You Need This Test?
Your healthcare provider might order this test if you have symptoms of infection (like fever, fatigue, or persistent sore throat), if you’re undergoing treatment for conditions like sepsis, leukemia, or autoimmune disorders, or if routine blood work suggests abnormal white blood cell counts.
What to Expect Before the Test
No special preparation is usually needed. You’ll have a small needle inserted into your arm or hand to draw blood. If you’re nervous, let your healthcare provider know—they can help make it more comfortable.
What Happens During the Test?
A healthcare professional will collect a small sample of your blood using a needle. The blood will be sent to a lab for analysis. The process typically takes a few minutes, and you may feel a slight pinch or sting.
Reference range
Reference ranges vary by laboratory and instrument platform; typical adult reference range is approximately 170-1100 cells/μL (or 0.17-1.10 x 10^9/L). CD14+ monocytes typically constitute 1.7-9.3% of total leukocytes.N/A
No special preparation required. Patient should be well-hydrated. Avoid recent immunosuppressive therapy if possible, as results may be affected. Inform provider of any recent infections or vaccinations.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
CD14+ Cells (Absolute)
Frequently asked questions
Why do doctors check CD14 levels?
What does a high CD14 count mean?
What if my CD14 count is low?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy