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CD14 Cells, Count in Whole Blood

Published: August 9, 2026Updated: August 16, 2026

This test measures the number of CD14-positive cells in your blood, which are a type of immune cell involved in detecting and responding to infections and inflammation.

Quick summary

["CD14 cells help your immune system fight infections and inflammation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
32507-6
Short code
CD14BM
Synonyms
CD14 Cells NFr Mar
Category
chemistry
Sample
serum
Container
Sterile bone marrow aspirate collection tube containing sodium heparin anticoagulant (green-top) or EDTA (lavender-top); specimen must be kept at room temperature and processed within established stability window
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
Flow cytometry using fluorescently labeled anti-CD14 monoclonal antibodies to identify and quantify CD14-positive monocytes/macrophages in bone marrow aspirate
CPT
88184
SNOMED
40610006
Specimen volume
1-3 mL of first-pull bone marrow aspirate collected in anticoagulant-containing tube
Stability
Specimen should be processed within 24 hours of collection when stored at room temperature (18-25°C); do not refrigerate or freeze as this may compromise cell viability and surface antigen integrity
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
24–72 hours
Order
routine

What Is CD14 Used For?

CD14 cells are a subset of monocytes, a type of white blood cell. They play a critical role in recognizing pathogens and initiating immune responses. This test may be used to evaluate immune function, monitor infections, or assess inflammatory conditions, though it is not routinely ordered for general health screening.

Why Might You Need This Test?

Your healthcare provider might order a CD14 cell count if you have symptoms of infection, autoimmune disease, or other conditions affecting immune cells. It can also be part of a broader evaluation for certain blood disorders or to monitor treatment responses.

How Is the Test Performed?

A small sample of your blood is drawn, typically from a vein in your arm. The blood is then analyzed in a laboratory to count the number of CD14-positive cells. This test is usually done using automated blood cell counters or flow cytometry.

What Do Results Mean?

Results are reported as an absolute cell count (number of CD14 cells per microliter of blood). While specific reference ranges vary by lab, abnormal counts may indicate immune system dysfunction, infection, or other underlying health issues. Your provider will interpret results in the context of your overall health and symptoms.

Reference range

Reference ranges for CD14+ cells in bone marrow vary by laboratory; typically expressed as percentage of total nucleated cells or absolute count. Results should be interpreted in conjunction with morphological evaluation and complete bone marrow differential.N/A

Specimen: serum

No special preparation required. Patient should follow standard pre-bone marrow aspiration protocols as directed by their physician. Avoid anticoagulant therapy if possible prior to procedure per institutional guidelines.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

CD14 Cell Count

Frequently asked questions

How often do I need this test?
This test is not a routine screening and is typically ordered only when there are specific clinical concerns, such as suspected infection, autoimmune disease, or monitoring of immune-related treatments. Your provider will determine the need based on your symptoms and medical history.
What are the normal values for this test?
There are no universally standardized reference ranges for CD14 cell counts alone, as they can vary by lab and patient factors. Your results will be compared to your individual baseline and clinical context. Abnormal values may suggest immune activation or dysfunction.
Can I prepare for this test?
No special preparation is needed for this blood test. You may have a light meal beforehand, but avoid heavy or fatty foods. If you are on blood thinners or have a history of bleeding disorders, inform your provider before the test.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy