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Bronchial Lavage Cell Differential Count

Published: August 9, 2026Updated: August 16, 2026

This test examines the types and proportions of cells collected from your airways, often used to assess lung inflammation, infection, or other respiratory conditions.

Quick summary

["Understanding your airway cell makeup can help diagnose or monitor lung health issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
56773-5
Short code
CD1a Bronch
Synonyms
CD1a Cells NFr Bronch
Category
chemistry
Sample
serum
Container
Sterile specimen container with saline or RPMI 1640 transport medium for cell preservation; 10% neutral buffered formalin for tissue biopsies designated for immunohistochemistry
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
Immunohistochemistry (IHC) with flow cytometry correlation; monoclonal antibody staining for CD1a surface marker detection
CPT
88342
SNOMED
39579001
Specimen volume
Bronchial washings: 5-10 mL minimum; bronchoalveolar lavage (BAL): 10-50 mL; biopsy tissue: representative sample of adequate cellularity
Stability
Fresh specimens for flow cytometry: process within 2-4 hours at room temperature (15-25°C); fixed tissue for IHC: stable in formalin for up to 48 hours before processing
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
48–120 hours
Order
routine

Why This Test Is Done

Your doctor may order this test if you have symptoms like persistent cough, shortness of breath, or unexplained lung problems. It helps identify whether inflammation, infection, or other conditions are affecting your airways by analyzing cells washed from your lungs.

What to Expect Before the Test

You’ll likely undergo a bronchoscopy, where a thin tube with a camera is inserted through your nose or mouth to reach your airways. A small amount of fluid is collected from your lungs, and cells are examined under a microscope.

What the Results Mean

The test looks at cell types like neutrophils (common in infections), lymphocytes (linked to chronic inflammation), eosinophils (often seen in allergies or asthma), and macrophages (indicative of chronic lung disease). Abnormal cell counts can signal conditions such as pneumonia, asthma, or interstitial lung disease.

Common Conditions Monitored

This test is often used to diagnose or monitor conditions like pneumonia, asthma, cystic fibrosis, or other inflammatory lung diseases. It helps track how well treatments are working or if symptoms are worsening over time.

Reference range

Reported as percentage of CD1a-positive cells or as a descriptive category (present/absent). Normal bronchial tissue may show scattered Langerhans cells expressing CD1a. Quantitative reference values are laboratory-specific; results should be interpreted in clinical context by a qualified pathologist.N/A

Specimen: serum

No special patient preparation required for the laboratory test itself. Specimen collection via bronchoscopy requires standard pre-procedure fasting and informed consent per institutional bronchoscopy protocol.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Bronchial Lavage Cell Types

Frequently asked questions

What causes abnormal cell counts in bronchial lavage?
Abnormal cell counts can result from infections (e.g., bacteria, viruses), allergies, chronic lung diseases (e.g., COPD, fibrosis), or exposure to irritants. For example, high neutrophils may indicate bacterial infection, while high eosinophils may suggest allergies or asthma.
How soon will I get my results?
Results are typically available within 24 to 48 hours, depending on lab processing times. Your doctor will discuss them with you during a follow-up visit.
Can I eat or drink before this test?
No special preparation is needed, but follow your doctor’s instructions regarding fasting or medications. You may need to stop certain medications (like blood thinners) beforehand if directed.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy