CD235A (Glycoprotein IIb/IIIa) on Platelet Surface
This test measures the presence of CD235A, a glycoprotein found on the surface of platelets, which plays a key role in blood clotting. It may be used to assess platelet function or detect certain blood disorders.
["CD235A helps identify platelet-related conditions and supports blood clotting evaluation."]
Key facts at a glance
- LOINC
- 33207-2
- Short code
- CD235a
- Synonyms
- CD235a Cells NFr Tiss
- Category
- chemistry
- Sample
- serum
- Container
- 10% neutral buffered formalin container for tissue specimens
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- Immunohistochemistry
- CPT
- 88342
- SNOMED
- 428191000124101
- Specimen volume
- Adequate tissue sample; minimum 3-5 mm tissue fragment in formalin
- Stability
- Formalin-fixed tissue stable at room temperature (15-25°C) for extended periods; paraffin-embedded blocks stable indefinitely at room temperature
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 48–72 hours
- Order
- routine
Why Might This Test Be Ordered?
Your healthcare provider may request this test if you have symptoms or conditions linked to abnormal platelet function, such as bleeding disorders, clotting issues, or unexplained bruising. It could also be part of a broader evaluation for conditions affecting blood cells or vascular health.
What Does the Test Involve?
A blood sample is taken from a vein, typically in your arm. The sample is then analyzed to detect CD235A on your platelets. This test does not require fasting or special preparation beyond standard blood draw procedures.
Sample and Testing Process
The blood sample is processed to isolate platelets, which are examined for the presence of CD235A using a specialized immunoassay method. This helps determine if the glycoprotein is functioning as expected on your platelets.
What Are Common Reasons for Testing?
Common reasons include diagnosing or monitoring conditions like thrombocytopenia (low platelet count), von Willebrand disease, or other inherited or acquired bleeding disorders. It may also be used in research or specialized clinical studies.
Reference range
Reported as percentage of CD235a (glycophorin A) positive cells in tissue; reference range varies by tissue type. Typically reported qualitatively or semi-quantitatively by pathologist assessment.N/A
No special patient preparation required for tissue specimens submitted for immunohistochemistry analysis.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Platelet Glycoprotein IIb/IIIa Expression
Frequently asked questions
What Does a Result Mean?
How Do I Prepare for This Test?
What Are the Possible Risks?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy