C-reactive protein (CRP) with 24-hour urinary excretion rate measurement
This test measures how much of the CRP protein appears in your urine over 24 hours, which can help assess inflammation or kidney function.
["CRP in urine helps track kidney health and inflammation over time."]
Key facts at a glance
- LOINC
- 90737-8
- Short code
- PNH-N
- Synonyms
- CD24-FLAER- cells/CD15 NFr Bld
- Category
- chemistry
- Sample
- whole-blood
- Container
- EDTA (lavender/purple-top) tube
- Units
- N/A
- Ref low
- 98
- Ref high
- 100
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- Flow cytometry using fluorescent aerolysin (FLAER) and fluorochrome-conjugated antibodies against CD24 and CD15
- CPT
- 86356
- SNOMED
- 44475005
- Specimen volume
- 3-5 mL whole blood (minimum 1 mL for pediatric samples)
- Stability
- Refrigerated (2-8°C): up to 48 hours. Do not freeze. Specimens should be processed within 24-48 hours of collection for optimal results
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 24–72 hours
- Order
- routine
Why CRP in Urine Matters
CRP (C-reactive protein) is a marker produced by your body in response to inflammation. While CRP in blood is commonly checked, measuring its urinary excretion can provide additional insight into how your kidneys process proteins and whether inflammation is affecting your urinary system.
What This Test Measures
This test quantifies the amount of CRP released into your urine over a full day. Elevated urinary CRP may indicate kidney issues, such as proteinuria (excess protein in urine), or systemic inflammation that your kidneys are filtering.
Common Causes of Abnormal Results
Higher-than-normal urinary CRP levels may be linked to kidney diseases (e.g., glomerulonephritis), certain infections, or conditions causing widespread inflammation. Lower-than-expected levels might suggest impaired kidney function or medications affecting protein excretion.
When You Might Need This Test
Your doctor may order this test if you have symptoms like persistent protein in urine, kidney-related concerns, or if you’re being monitored for chronic inflammation or kidney disease.
Reference range
≥98% of neutrophils normally express CD24 and bind FLAER. Decreased CD24-FLAER expression on neutrophils (typically <98%) is suggestive of paroxysmal nocturnal hemoglobinuria (PNH) or PNH cloneN/A
No fasting required. Avoid recent blood transfusion within 24-48 hours if possible, as donor cells may affect results. Inform laboratory of any recent transfusion history
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
CRP Urine Rate
Frequently asked questions
How often will I need to provide a urine sample for this test?
Will fasting be required before this test?
What are the typical reference ranges for this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy