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CD2-Positive Blasts-to-Total Blasts Ratio, Whole Blood — Flow Cytometry

Published: August 9, 2026Updated: August 17, 2026

Measures the proportion of circulating blast cells that carry the CD2 protein, which can help classify certain leukemias or lymphomas.

Quick summary

["This result shows what fraction of blood blasts express CD2 and is interpreted together with other leukemia tests."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
13841-2
Short code
CD2 Blasts/Blasts NFr Bld
Synonyms
CD2 Blasts/Blasts NFr Bld
Category
liver
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84484
SNOMED
302774002
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This test measures the proportion of immature blood cells, called blasts, that have the CD2 protein on their surface. CD2 is a cell-surface marker found on many T lymphocytes and on blasts in some types of leukemia or lymphoma.

Why might I need this test?

This test may be ordered when blood counts, symptoms, or other findings suggest a leukemia or lymphoma. It helps characterize blast cells and can provide information about the likely cell lineage or type of blood cancer.

How is the test performed?

A fresh whole-blood sample is analyzed using flow cytometry, which identifies cells and their surface markers. The laboratory reports the proportion of total blasts that are CD2-positive.

How do I prepare for the test?

No special preparation is usually required. Follow any instructions from the laboratory, and tell the healthcare team if you recently had a blood transfusion or received certain chemotherapy or antibody treatments, because these can affect cell testing.

Reference range

Adult: 10-40 U/LN/A

Specimen: whole-blood

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A higher proportion of CD2-positive blasts may be seen in certain T-cell or lymphoid leukemias and lymphomas, but this finding is not diagnostic by itself. A lower proportion may indicate that the blasts do not express CD2 or express it at a level below detection. Results must be interpreted with the blood count, cell appearance, and other flow-cytometry markers.

Short name

CD2 blast ratio

Frequently asked questions

What does a CD2-positive blast mean?
It is an immature blood cell that carries the CD2 surface protein. CD2 is commonly present on T cells, so its presence helps classify certain blood cancers.
Does this test diagnose leukemia by itself?
No. It is one part of a broader evaluation that may include blood counts, a blood smear, flow cytometry, genetic testing, and sometimes a bone marrow examination.
Why might my result be difficult to interpret?
Recent chemotherapy, antibody treatments, or a blood transfusion can change the blood-cell population being measured. Your healthcare provider will interpret the result in the context of your treatment history and other findings.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy