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CD2-Positive Blasts, Bone Marrow — Number Fraction

Published: August 9, 2026Updated: August 17, 2026

Measures the proportion of bone marrow blast cells that carry the CD2 protein, which can help classify certain blood cancers.

Quick summary

["This flow cytometry test shows how many marrow blasts have CD2 on their surface."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
51110-5
Short code
CD2 Blasts/Blasts NFr Mar
Synonyms
CD2 Blasts/Blasts NFr Mar
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

Blasts are immature blood-forming cells. This test measures the fraction of blasts in a bone marrow sample that express CD2, a protein found on the surface of some immune cells. It is commonly used as part of the flow cytometry evaluation of leukemia or lymphoma.

Why might I need this test?

A clinician may order this test to identify and classify abnormal white blood cells, especially when leukemia or lymphoma is suspected. The CD2 pattern may be combined with other cell markers to determine the likely type of blood cancer.

How is the test performed?

A small bone marrow sample is collected and analyzed by flow cytometry. The laboratory counts the marrow blasts and determines what proportion of them carry CD2.

How do I prepare for the test?

No medication or dietary preparation is usually required. Bone marrow collection is performed by a trained clinician, and you may be asked about bleeding problems, medications, and allergies beforehand.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

An increased proportion of CD2-positive blasts may be seen in some forms of leukemia or lymphoma. However, this result is not diagnostic by itself and must be interpreted with the overall cell pattern, other laboratory findings, and the clinical situation.

Short name

CD2-positive blasts, bone marrow

Frequently asked questions

Does a positive result mean I have cancer?
No. CD2-positive blasts can have several meanings, and the result must be interpreted alongside the percentage of blasts, other immune markers, symptoms, and other tests.
What does “number fraction” mean?
It means the proportion of all blasts in the marrow sample that carry the CD2 marker, rather than an absolute count per unit of blood.
Is bone marrow collection painful?
It may cause brief discomfort, particularly during the procedure, and soreness afterward. Local anesthetic is generally used, and the clinician can discuss options for reducing discomfort.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy