Skip to content

Quantitative measurement of CD2 cells in tissue

Published: August 9, 2026Updated: August 16, 2026

This test helps assess the number of CD2-positive cells, which are a type of immune system cell found in tissues. CD2 cells play a role in immune signaling and activation.

Quick summary

["CD2 cells are part of your immune system and may be checked if you have symptoms of immune-related conditions or after certain treatments."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
43951-3
Short code
CD2T
Synonyms
CD2 Cells # Tiss
Category
chemistry
Sample
serum
Container
Sterile tissue collection container in appropriate transport medium (e.g., RPMI 1640 or saline). EDTA tubes may be used for associated blood specimens.
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
Flow Cytometry (Immunophenotyping) - CD2 surface marker enumeration using fluorescently labeled monoclonal antibodies
CPT
86356
SNOMED
399660006
Specimen volume
Tissue biopsy: minimum 0.5-1 cm³ fresh tissue. Adequate cellularity required for flow cytometric analysis.
Stability
Fresh tissue should be processed within 24-48 hours of collection when stored at 2-8°C. Viability of cells decreases significantly after 48 hours.
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
24–72 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may order this test if you have symptoms like chronic infections, autoimmune diseases, or if you’ve received treatments that affect immune cells. It can also be part of monitoring for conditions like lymphoma or other immune disorders.

What to Expect Before the Test

No special preparation is typically needed. If a tissue sample is taken (e.g., biopsy), your provider will explain the process and any precautions, such as fasting or avoiding certain medications.

How the Test Works

A small sample of tissue is collected and analyzed in a lab. The lab will count and measure CD2 cells using advanced techniques, such as flow cytometry or immunohistochemistry, to determine the concentration.

What the Results Mean

Results may show whether CD2 cell levels are higher or lower than expected. Abnormal results could indicate immune system changes, inflammation, or other underlying health issues that need further evaluation.

Reference range

Reference ranges for CD2+ cells in tissue vary significantly by tissue type and clinical context. Values should be interpreted in conjunction with clinical findings and compared to laboratory-specific reference intervals.N/A

Specimen: serum

No special preparation required. Specimen collection depends on tissue type being evaluated (e.g., biopsy, bone marrow aspirate).

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Changes in CD2 cell counts can help diagnose or monitor conditions affecting immune function, such as immune deficiencies, certain cancers (e.g., T-cell lymphomas), or responses to therapies like chemotherapy or biologics. High or low counts may signal different health risks.

Short name

CD2 Cell Count in Tissue

Frequently asked questions

What does a CD2 cell count test measure?
This test measures the number of CD2-positive cells in a tissue sample, which are a subset of immune cells involved in signaling and activation. It’s not a general blood test but focuses on tissue-based immune assessment.
How is the tissue sample collected for this test?
The sample is usually taken through a biopsy, where a small piece of tissue is removed from your body (e.g., skin, lymph node, or other affected area). Your provider will explain the procedure and any risks involved.
Can diet or medications affect this test?
No specific diet or medications are typically restricted for this test, as it involves tissue analysis rather than blood or urine samples. However, always inform your provider about any medications or supplements you’re taking.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy