CD3+ T Cell Count (Absolute)
This test measures the number of CD3+ T cells in your blood, which are a type of white blood cell important for immune function.
["CD3+ T cells help fight infections and regulate immune responses."]
Key facts at a glance
- LOINC
- 107083-8
- Short code
- CD3CD26
- Synonyms
- CD3+CD26+ Cells NFr Bld FC
- Category
- chemistry
- Sample
- whole-blood
- Container
- EDTA (lavender/purple-top) anticoagulant tube; ACD (yellow-top) tube is also acceptable
- Units
- N/A
- Ref low
- 5
- Ref high
- 15
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- flow-cytometry
- CPT
- 86359
- SNOMED
- 396881000
- Specimen volume
- 3-5 mL of whole blood; minimum 1 mL for pediatric samples
- Stability
- Specimen should be processed within 24-30 hours of collection when stored at room temperature (18-25°C). Refrigeration (2-8°C) may extend stability to 48 hours but may affect some surface marker expression. Do not freeze.
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 24–72 hours
- Order
- routine
What Are CD3+ T Cells?
CD3+ T cells are a subset of lymphocytes (a type of white blood cell) that play a central role in the immune system. They help identify and destroy pathogens like viruses and bacteria, as well as regulate other immune responses. CD3 is a protein marker found on all T cells, making this test useful for assessing overall T cell activity.
Why Might You Need This Test?
Doctors may order a CD3+ T cell count to evaluate immune function, diagnose conditions like immunodeficiency, or monitor treatment responses in diseases such as HIV, autoimmune disorders, or certain cancers. It can also help assess how well your immune system is responding to infections or medications.
How Is This Test Performed?
A blood sample is drawn from a vein, usually in your arm. The sample is then analyzed in a lab to count the number of CD3+ T cells present. This test is typically done using flow cytometry, a technique that separates and counts different types of blood cells based on their markers.
What Do Results Mean?
Results are usually reported as a count of CD3+ T cells per microliter (cells/µL) of blood. Lower than expected counts may indicate immune deficiencies or conditions affecting T cell production or function. Higher counts may sometimes be seen in certain infections or inflammatory states, but this is less common.
Reference range
Reference values for CD3+CD26+ cells in peripheral blood vary by laboratory and reporting unit (cells/μL or percentage of lymphocytes). Typical adult ranges: 5-15% of total lymphocytes or 80-400 cells/μL. Pediatric values are generally higher than adult values.N/A
No special preparation required. Patients should inform their healthcare provider of any recent corticosteroid, immunosuppressive, or immunomodulatory therapy, as these may affect lymphocyte subset counts. Recent vaccinations may transiently alter results.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
CD3+ T Cells
Frequently asked questions
How often will I need this test?
What are the normal ranges?
Can lifestyle changes affect this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy