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Lymphocyte count in peripheral blood (absolute count)

Published: August 9, 2026Updated: August 16, 2026

This test measures the number of lymphocytes, a type of white blood cell, in your blood. Lymphocytes help fight infections and are part of your immune system.

Quick summary

["Lymphocytes help protect your body from illness and infection."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
97596-1
Short code
CD3CD8LR
Synonyms
CD3+CD8+ Cells/lymph NFr Lower resp FC
Category
chemistry
Sample
serum
Container
Sterile, leak-proof container for bronchoalveolar lavage (BAL) or bronchoalveolar washings; transport at 2-8°C to preserve cell viability; recommended within 24 hours of collection
Units
N/A
Ref low
15
Ref high
40
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
flow-cytometry
CPT
86360
SNOMED
115006000
Specimen volume
Minimum 5-10 mL of bronchoalveolar lavage fluid; larger volumes (20-50 mL) preferred when possible for adequate cell yield
Stability
Specimen should be processed within 2-4 hours of collection for optimal viability. If processing is delayed, store at 2-8°C and process within 24 hours. Do not freeze.
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your doctor may order this test to check for infections, monitor immune function, or evaluate conditions like leukemia, lymphoma, or immune deficiencies. It can also help assess responses to treatments for blood disorders or autoimmune diseases.

What to Expect Before the Test

No special preparation is needed for this test. You’ll have a small needle inserted into your arm or hand to draw a blood sample. The process usually takes a few minutes, and you may feel a slight pinch or discomfort.

What the Test Results Mean

Lymphocyte counts can vary based on your overall health, age, and medical conditions. Low counts may suggest immune problems, while high counts could indicate infections, inflammation, or certain cancers. Your doctor will interpret the results in the context of your health history.

Common Conditions Monitored

This test is often used to monitor conditions like chronic infections (e.g., HIV), autoimmune diseases (e.g., lupus), or blood cancers (e.g., lymphoma). It can also help diagnose or track treatment progress in cases of immune system disorders.

Reference range

Reference ranges vary by laboratory and patient population. Typical adult reference ranges for CD3+CD8+ lymphocytes as a percentage of total lymphocytes: 15-40% (or 150-1000 cells/μL absolute count). Lower respiratory specimen values should be interpreted in clinical context.N/A

Specimen: serum

No special patient preparation required. Patients should follow standard pre-procedure instructions for lower respiratory specimen collection (e.g., bronchoscopy or bronchoalveolar lavage). Inform physician of any recent corticosteroid use, immunosuppressive medications, or chemotherapy, as these may affect results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Lymphocyte count

Frequently asked questions

How often will I need this test?
The frequency depends on your health condition and treatment plan. Some patients need this test regularly (e.g., monthly or quarterly) to monitor their immune system or cancer treatment response. Others may only need it once or twice a year if stable.
What are typical reference ranges?
Reference ranges for lymphocyte counts vary by lab and age. Generally, healthy adults may have counts between 1,500 and 4,500 cells per microliter of blood, but these numbers can shift with health changes. Your doctor will use your specific results alongside your overall health.
Can lifestyle changes affect my lymphocyte count?
Yes, lifestyle factors like diet, stress, sleep, and exercise can influence lymphocyte levels. Avoiding smoking, managing stress, and maintaining a balanced diet may support immune health, but results depend on your individual health status and any underlying conditions.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy