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CD3+ T Cell Count (Peripheral Blood)

Published: August 9, 2026Updated: August 16, 2026

This test measures the number of CD3+ T cells in your blood, which are a type of white blood cell important for immune function.

Quick summary

["CD3+ T cells help fight infections and regulate immune responses."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
101643-5
Short code
CD3 Cells p COVID NuclCap # Bld
Synonyms
CD3 Cells p COVID NuclCap # Bld
Category
coagulation
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What Is CD3+ T Cell Count Used For?

Doctors may order this test to evaluate your immune system, especially if you have symptoms like frequent infections, unexplained fatigue, or immune-related conditions. It can also help monitor treatment responses in certain diseases, such as autoimmune disorders or cancers like leukemia.

How Is the Test Performed?

A small blood sample is drawn from a vein, typically in your arm. The blood is then analyzed in a lab to count the CD3+ T cells. This is usually done using a specialized blood test that separates and identifies different types of white blood cells.

Preparation for the Test

No special preparation is needed for this test. You can eat, drink, and go about your normal activities as usual. If you are on certain medications or have a condition that might affect your immune system, let your healthcare provider know before the test.

What Are the Possible Results?

Results are typically reported as a count of CD3+ T cells per microliter (µL) of blood. While specific reference ranges can vary by lab, lower than expected counts may suggest immune deficiencies or certain diseases, while higher counts might be seen in certain infections or inflammatory conditions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

CD3 T Cell Count

Frequently asked questions

Why might my doctor want to check my CD3+ T cell count?
Your doctor may order this test if you have symptoms like repeated infections, unusual fatigue, or if you are undergoing treatment for conditions that affect the immune system, such as cancer, autoimmune diseases, or HIV. It can also help monitor immune function during treatment for diseases like leukemia or lymphoma.
What could abnormal results mean?
A lower than normal CD3+ T cell count might indicate a weakened immune system, which can make you more susceptible to infections. This could be due to genetic conditions, certain medications, or diseases like HIV/AIDS. A higher count may be seen in conditions like certain infections or autoimmune responses but should be evaluated by your healthcare provider.
How often will I need this test?
The frequency of this test depends on your health condition and treatment plan. Your doctor will determine how often you need follow-up tests based on your specific situation and medical history.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy