Platelet CD62P (P-selectin) Expression in Platelets by Flow Cytometry
This test measures the presence of P-selectin, a protein on the surface of platelets that helps them clump together during bleeding or injury. It’s often checked to assess platelet activation.
["P-selectin helps identify if your platelets are responding to injury or inflammation."]
Key facts at a glance
- LOINC
- 32746-0
- Short code
- CD62P
- Synonyms
- CD62P Cells NFr Spec
- Category
- chemistry
- Sample
- serum
- Container
- Sodium citrate (3.2%) anticoagulated tube (light blue top); CTAD tube preferred for minimizing platelet activation during collection
- Units
- N/A
- Ref low
- 0
- Ref high
- 5
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–99 years
- Method
- Flow cytometry using fluorescently labeled monoclonal antibodies directed against CD62P (P-selectin) surface antigen on activated platelets
- CPT
- 86022
- SNOMED
- 409620001
- Specimen volume
- 3-5 mL whole blood collected in citrate anticoagulant
- Stability
- Specimen should be processed within 1 hour of collection. If immediate processing is not possible, samples should be maintained at room temperature (18-24°C) and analyzed within 4 hours. Do not refrigerate or centrifuge before staining.
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your doctor may order this test if you have symptoms like easy bruising, prolonged bleeding, or unexplained clots. It can also help evaluate conditions affecting platelet function, such as certain blood disorders or after trauma.
What to Expect Before the Test
No special preparation is needed. You’ll have a small needle inserted into a vein, usually in your arm, to draw a small amount of blood. The process is quick and usually painless.
What the Test Results Mean
Higher than normal levels may suggest platelet activation due to injury, inflammation, or certain medications. Lower levels might indicate platelet dysfunction or other underlying issues. Your doctor will discuss results with you based on your symptoms and medical history.
Common Conditions Monitored
This test is often used to monitor platelet activation in conditions like thrombocytopenia purpura, von Willebrand disease, or after surgeries or trauma that may affect platelet function.
Reference range
Reference ranges are laboratory-specific and should be established by each facility. Typically expressed as percentage of platelets expressing CD62P or as mean fluorescence intensity (MFI). General indicative ranges: <5% resting platelets positive for CD62P in healthy individuals.N/A
No special patient preparation required. Patients should avoid strenuous exercise prior to specimen collection. Antiplatelet medications (aspirin, clopidogrel, NSAIDs) may affect results and should be documented.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
P-selectin Expression on Platelets
Frequently asked questions
What causes elevated P-selectin levels?
How long does it take to get results?
Can I eat or drink before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy