CD71 Antigen (Fc Receptor IIIa) in Whole Blood
This test measures the presence of CD71, a protein found on certain blood cells and tissues, which plays a role in iron metabolism and cell growth. It may be used to assess conditions affecting these processes.
["CD71 levels can help diagnose or monitor certain blood disorders or metabolic conditions."]
Key facts at a glance
- LOINC
- 29340-7
- Short code
- CD71
- Synonyms
- CD71 Cells # Bld
- Category
- chemistry
- Sample
- whole-blood
- Container
- Lavender-top (EDTA) or sodium heparin tube for flow cytometry; EDTA preferred for cell surface marker analysis
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- ≥ 0 years
- Method
- Flow cytometry using fluorescently-labeled monoclonal antibodies against CD71 (transferrin receptor)
- CPT
- 86356
- SNOMED
- 395124003
- Specimen volume
- 3-5 mL of whole blood for adults; minimum 1 mL for pediatric patients
- Stability
- Specimen should be processed within 24-48 hours of collection when stored at room temperature (18-25°C). Refrigeration may affect antigen expression. Best results obtained when analyzed within 24 hours.
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms or conditions linked to abnormal CD71 levels, such as anemia, certain cancers, or metabolic disorders. It could also be part of a broader evaluation for unexplained fatigue, weight changes, or other symptoms.
What to Expect Before the Test
No special preparation is typically required. You may fast for 8–12 hours before the test if instructed, but always follow your provider’s specific instructions. Bring any medications you’re taking to your appointment.
How the Test Is Performed
A healthcare professional will draw blood from a vein in your arm using a small needle. You may feel a brief sting, but the process usually takes just a few minutes. The blood sample is then sent to a lab for analysis.
What the Results Mean
Results are qualitative (present or absent) rather than numerical, meaning they indicate whether CD71 is detected in your blood. Your provider will interpret the results in the context of your medical history and symptoms to determine next steps.
Reference range
Reference ranges vary by age and laboratory; CD71+ cells are typically reported as cells/µL or cells/L. Normal adult values should be established by the performing laboratory. CD71 expression is typically higher in neonates and declines with age.N/A
No special patient preparation is required. However, recent blood transfusion, erythropoietin therapy, or treatment for anemia may affect results. Inform the laboratory of any recent therapy.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
CD71 Blood Test
Frequently asked questions
What causes CD71 to be tested?
Is fasting required for this test?
How long does it take to get results?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy