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Absolute CD8+ T-Cell Count (Per Microliter)

Published: August 9, 2026Updated: August 16, 2026

This test measures the number of CD8+ T-cells in your blood, a type of immune cell that helps fight infections and cancer. CD8+ T-cells are part of your adaptive immune system and play a role in targeting and destroying infected or abnormal cells.

Quick summary

["CD8+ T-cells help protect your body by identifying and attacking harmful cells, so this count can indicate immune health or response to treatments."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
17204-9
Short code
CD87
Synonyms
CD87 Cells NFr Bld
Category
chemistry
Sample
whole-blood
Container
EDTA (lavender-top) tube for flow cytometry
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
0–999 years
Method
Flow cytometry using fluorescently labeled monoclonal antibodies targeting CD87 (urokinase plasminogen activator receptor, uPAR)
CPT
86356
SNOMED
27070000
Specimen volume
3-5 mL whole blood; minimum 1 mL for pediatric samples
Stability
Process within 24 hours of collection at room temperature (18-25°C); do not refrigerate as this may affect cell viability and marker expression
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
24–72 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may order this test if you have symptoms of immune disorders, such as frequent infections, unexplained fatigue, or if you’re undergoing treatment for conditions like HIV, cancer, or autoimmune diseases. It can also be used to monitor immune function before or after certain therapies.

What to Expect Before the Test

No special preparation is usually needed. You may have a small needle inserted into a vein in your arm to draw blood. This is typically done in a clinic or lab setting and takes about 5–10 minutes. Avoid strenuous activity or eating/drinking for 2–3 hours before the test if instructed.

What Happens During the Test

A healthcare professional will collect a blood sample from a vein in your arm. The blood will be sent to a lab, where it is analyzed to count your CD8+ T-cells. The results are usually available within 1–3 business days.

What the Results Mean

Results are reported as a count of CD8+ T-cells per microliter (µL) of blood. Lower-than-expected counts may suggest immune suppression, while higher-than-expected counts could indicate certain immune conditions or responses to treatments. Your provider will interpret the results in the context of your overall health.

Reference range

Reference values vary by laboratory; results typically reported as percentage of cells expressing CD87 or as cells per unit volume. Generally reported qualitatively or semi-quantitatively in clinical contexts.N/A

Specimen: whole-blood

No special patient preparation required. Samples should be collected by standard venipuncture or capillary puncture techniques.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: CD8+ T-Cell Counts in Health and Disease

Short name

CD8+ T-Cell Count

Frequently asked questions

How often should I get this test?
The frequency depends on your medical condition and treatment plan. If you’re monitoring an immune-related illness or undergoing therapy (e.g., chemotherapy, HIV treatment), your provider may recommend regular testing. For general health, this test is rarely routine unless symptoms or risk factors suggest it.
What do abnormal results mean?
Low CD8+ T-cell counts may indicate weakened immunity, often seen in HIV/AIDS, certain cancers, or after treatments like chemotherapy. High counts could be linked to chronic infections, autoimmune disorders, or certain immune responses. Always discuss results with your healthcare provider for personalized insights.
Can lifestyle changes affect this test?
Yes, lifestyle factors like diet, stress, and sleep can influence immune cell counts. Avoiding excessive alcohol, maintaining a balanced diet, and managing stress may support immune health, but this test specifically measures absolute cell counts, so results are based on lab analysis rather than direct lifestyle impact.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy