Cyclin-dependent kinase 1B (CDKN1B) mass concentration (serum/plasma)
This test measures the amount of Cyclin-dependent kinase 1B protein in your blood. It may be used to assess certain genetic or metabolic conditions.
["Measuring CDKN1B helps evaluate genetic predispositions or metabolic functions, though it’s not commonly ordered for routine testing."]
Key facts at a glance
- LOINC
- 75388-9
- Short code
- CDKN1BFM
- Synonyms
- CDKN1B Fam Mut Anl Bld/T
- Category
- chemistry
- Sample
- whole-blood
- Container
- EDTA tube (lavender-top) for whole blood; sterile container with appropriate preservative for tissue specimens
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- ≥ 0 years
- Method
- molgen
- CPT
- 81223
- SNOMED
- 430925001
- Specimen volume
- Whole blood: 3-5 mL; Tissue: minimum 5 mg fresh tissue or paraffin-embedded tissue block
- Stability
- Whole blood: Room temperature 24 hours, refrigerated (2-8°C) for 7 days, frozen (-20°C or below) for longer storage. Tissue: Formalin-fixed paraffin-embedded (FFPE) tissue stable indefinitely at room temperature; fresh tissue should be frozen at -80°C for long-term storage.
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 168–720 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms or a family history suggestive of conditions linked to CDKN1B, such as certain cancers or metabolic disorders. It could also be part of research or specialized diagnostic testing.
What to Expect Before the Test
No special preparation is typically required. You may fast or avoid certain medications for 12 hours before the draw, but always follow your provider’s instructions. Bring any medications you’re currently taking.
How the Test Works
A blood sample is collected from a vein in your arm. The sample is sent to a lab where it is analyzed to measure the concentration of CDKN1B protein using advanced techniques like mass spectrometry.
What the Results Mean
Results are compared to a reference range specific to the lab. Elevated or low levels may indicate underlying health concerns, but interpretation depends on clinical context, including your medical history and symptoms.
Reference range
Negative for known familial CDKN1B mutations. Result reported as Mutation Detected or Mutation Not Detected for each familial mutation tested.N/A
No fasting required. Patient should be informed about the genetic nature of the test and provide informed consent prior to specimen collection. Genetic counseling is recommended before and after testing.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
CDKN1B Serum/Plasma
Frequently asked questions
CDKN1B is a protein involved in cell cycle regulation and may play a role in cancer development or metabolic processes. Abnormal levels could suggest genetic mutations, inherited conditions, or metabolic disorders, but further testing and clinical correlation are needed.
Will I need to prepare differently if I’m pregnant or on certain medications?
How long will I wait for my results?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy