Monosialocerbroside and Disialocerbroside in Serum (Quantitative)
This test measures specific types of glycolipids—complex molecules found in cell membranes—using serum. These lipids are important in nerve cell function and may be studied in conditions affecting the nervous system.
["Helpful for diagnosing or monitoring rare genetic or neurological conditions linked to lipid metabolism."]
Key facts at a glance
- LOINC
- 44732-6
- Short code
- CDT-MS-DS
- Synonyms
- CDT Monosialo/CDT Disialo SerPl
- Category
- chemistry
- Sample
- serum
- Container
- Red-top serum tube or serum separator tube (SST)
- Units
- N/A
- Ref low
- 0
- Ref high
- 0.05
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- High-Performance Liquid Chromatography (HPLC) or Capillary Electrophoresis with Immunodetection
- CPT
- 82373
- SNOMED
- 395146003
- Specimen volume
- 1-2 mL serum
- Stability
- Room temperature: 24 hours; Refrigerated (2-8°C): 7 days; Frozen (-20°C or below): 30 days
- Hemolysis max
- 100
- Lipemia max
- 50
- Icterus max
- 50
- TAT
- 48–168 hours
- Order
- routine
Why This Test Is Done
Your healthcare provider may order this test if you have symptoms like developmental delays, movement disorders, or neurological issues. It could also be part of research studies or specialized diagnostic workups for inherited lipid disorders.
What to Expect Before the Test
No special preparation is needed. You’ll provide a blood sample drawn from a vein, similar to other routine blood tests. If you’re on blood thinners, let your provider know to avoid excessive bruising.
What the Results Mean
Results compare your lipid levels to a reference range for healthy individuals. Abnormal levels may suggest conditions like gangliosidosis or other rare metabolic disorders affecting nerve cells.
Common Conditions Monitored
This test is primarily used in research or specialized clinical settings for diagnosing rare genetic disorders. It’s not routinely ordered for general health checks.
Reference range
Ratio <0.05 (normal); elevated ratios suggest congenital disorders of glycosylation (CDG) or alcohol-related isoform shiftsN/A
No special preparation required. Recent blood transfusion may affect results. Alcohol consumption within 7-10 days may elevate carbohydrate-deficient transferrin isoforms.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance: This test evaluates specific glycolipids (monosialocerbroside and disialocerbroside) in serum, which are components of nerve cell membranes. Abnormalities may indicate inherited metabolic disorders affecting nerve function, such as GM1 gangliosidosis or other lysosomal storage diseases. Results are interpreted by a specialist in metabolic or genetic disorders.
Short name
Monosialocerb/Disialocerb Levels
Frequently asked questions
What does a high or low result mean?
Is this test covered by insurance?
How often can I get this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy