Fucose, pentasialohexasialo (Fuc-P5H6) in Serum/Plasma
This test measures the presence of specific sugar (glycosylation) modifications on fucose in your blood, which can reflect how proteins are attached to sugars in your body.
["This test helps assess how well your body's proteins are modified with sugars, which can be important for certain conditions."]
Key facts at a glance
- LOINC
- 76613-9
- Short code
- CDT56
- Synonyms
- CDT pentasialo+hexasialo/Tf MFr SerPl
- Category
- chemistry
- Sample
- serum
- Container
- Red-top serum tube (no anticoagulant) or serum separator tube (SST)
- Units
- N/A
- Ref low
- 0
- Ref high
- 2.5
- Critical range
- — – 3 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- High-Performance Liquid Chromatography (HPLC) or Capillary Electrophoresis (CE) with immunoassay-based detection
- CPT
- 82373
- SNOMED
- 395146007
- Specimen volume
- 1.0-2.0 mL of serum
- Stability
- Stable for 7 days at 2-8°C; for extended storage, freeze at -20°C or below for up to 3 months. Avoid repeated freeze-thaw cycles.
- Hemolysis max
- 100
- Lipemia max
- 100
- Icterus max
- 50
- TAT
- 24–72 hours
- Order
- routine
What Does This Test Measure?
The test detects fucose molecules that have been attached to specific sugar chains (pentasialo and hexasialo forms) on proteins in your blood. These modifications can vary depending on health, genetics, or disease processes.
Why Might This Test Be Ordered?
Your healthcare provider may order this test to evaluate conditions affecting protein glycosylation, such as certain genetic disorders, immune system issues, or metabolic conditions. It may also be used in research or specialized diagnostic scenarios.
What Does the Result Mean?
Results are not typically provided as a single numeric value in this format. Instead, they may be qualitative (present/absent) or compared to reference ranges specific to the laboratory’s methods. Interpretation depends on clinical context and may require consultation with a specialist.
Common Uses and Conditions
This test is less commonly used in routine clinical practice but may be part of advanced diagnostics for rare conditions like certain lysosomal storage diseases or immune deficiencies. It can also be used in research settings to study protein glycosylation.
Reference range
Pentasialo + Hexasialo transferrin fraction is typically expressed as a percentage of total transferrin. Normal range: less than 2.5% of total transferrin. Values above 2.5% may suggest carbohydrate-deficient transferrin (CDT) patterns associated with chronic alcohol consumption or congenital disorders of glycosylation.N/A
No special preparation required. However, patients should abstain from alcohol consumption for at least 2 weeks prior to testing for accurate assessment of alcohol-related carbohydrate-deficient transferrin patterns.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
Fucose glycosylation profile
Frequently asked questions
What causes changes in fucose glycosylation levels?
How long does it take to get results from this test?
Is this test painful or invasive?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy