Cdttrisialocdttetrasialoserpl
Key facts at a glance
- LOINC
- 90420-1
- Short code
- CDT33_44
- Synonyms
- CDT Trisialo/CDT Tetrasialo SerPl
- Category
- chemistry
- Sample
- serum
- Container
- Serum separator tube (SST) or red-top vacutainer tube; plasma may be collected in lithium heparin or EDTA tubes
- Units
- N/A
- Ref low
- 0
- Ref high
- 0.05
- Critical range
- — – 0.1 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- ≥ 18 years
- Method
- High-performance liquid chromatography (HPLC) or capillary electrophoresis for separation and quantification of transferrin isoforms; immunodetection methods may also be used. The trisialo/tetrasialo ratio is calculated from chromatographic peak areas or electrophoretic band intensities.
- CPT
- 82977 (Glutamine); CDT testing commonly billed under 82373 or as part of carbohydrate-deficient transferrin panel; verify with current payer guidelines
- SNOMED
- 313471003 |Measurement of carbohydrate-deficient transferrin ratio| or related transferrin isoform SNOMED codes
- Specimen volume
- 1-2 mL of serum or plasma
- Stability
- Room temperature: 7 days; Refrigerated (2-8°C): 14 days; Frozen (-20°C or below): 6 months. Avoid repeated freeze-thaw cycles.
- Hemolysis max
- 50
- Lipemia max
- 100
- Icterus max
- 25
- TAT
- 24–96 hours
- Order
- routine
Reference range
Trisialo/Tetrasialo transferrin ratio: typically <0.05 (or <5%) in healthy individuals with normal alcohol consumption. Values are interpreted as part of the complete carbohydrate-deficient transferrin (CDT) profile including asialo-, monosialo-, and disialo-transferrin fractions.N/A
No fasting required. Patients should abstain from alcohol for at least 2 weeks prior to testing for accurate assessment of alcohol-related changes, as transferrin glycosylation normalizes within 2-4 weeks of abstinence. Inform laboratory of any recent transfusions, iron supplementation, or liver disease diagnosis.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 11, 2026. · Read our editorial policy