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D-dimer (Plasma) with Flow Cytometry Immunoassay

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of D-dimer, a protein fragment produced when blood clots break down. It helps assess whether you’re at risk for blood clots or clot-related conditions.

Quick summary

["D-dimer helps identify potential blood clotting risks or recent clot dissolution."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
101989-2
Short code
CDNABF
Synonyms
C dubliniensis DNA Fld Ql Probe.amp.tar
Category
chemistry
Sample
serum
Container
Sterile, DNA-free, leak-proof container; serum separator tube (SST) or sterile cryovial for body fluid specimens
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
CPT
87798
SNOMED
122450004
Specimen volume
1-2 mL of serum or body fluid
Stability
Refrigerated (2-8°C): up to 7 days; Frozen (-20°C or below): up to 4 weeks. Avoid repeated freeze-thaw cycles. Transport at 2-8°C if testing within 48 hours.
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
24–72 hours
Order
routine

Why Is This Test Done?

Your doctor may order a D-dimer test to evaluate symptoms like unexplained shortness of breath, chest pain, leg swelling, or unexplained bruising. It’s also used to check for conditions like deep vein thrombosis (blood clots in veins) or pulmonary embolism (clots in the lungs).

What to Expect During the Test

A small blood sample is drawn from a vein, usually in your arm. The blood is processed to measure D-dimer levels. This is a quick and painless procedure.

How the Results Are Interpreted

High D-dimer levels may suggest recent clot formation, while low or normal levels help rule out clotting disorders. Your doctor will interpret results in the context of your symptoms and medical history.

Common Conditions Monitored

D-dimer is often used to diagnose or monitor conditions like venous thromboembolism, disseminated intravascular coagulation (DIC), or to assess patients with suspected clotting disorders.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: serum

No special patient preparation required. Specimen collection should occur prior to initiation of antifungal therapy when possible, as treatment may reduce pathogen DNA load and yield false-negative results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: D-dimer plays a key role in diagnosing blood clots and evaluating clot-related complications. Elevated levels can indicate recent clot activity, guiding treatment decisions such as anticoagulant therapy.

Short name

D-dimer

Frequently asked questions

What causes elevated D-dimer levels?
Elevated D-dimer levels can result from conditions like blood clots (thrombosis), inflammation, trauma, surgery, or certain cancers. It’s not specific to one condition, so results should be reviewed with your doctor.
What if my D-dimer test is positive?
A positive D-dimer test suggests a higher likelihood of blood clots but isn’t definitive. Your doctor may recommend further testing (like imaging or additional blood tests) to confirm or rule out conditions like deep vein thrombosis or pulmonary embolism.
Can lifestyle changes affect D-dimer levels?
While lifestyle factors like physical activity, diet, and smoking may influence overall clotting tendencies, D-dimer levels are primarily tied to recent clot activity. Your doctor will consider your overall health and medical history when interpreting results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy