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C-reactive protein, serum concentration (high-sensitivity)

Published: August 9, 2026Updated: August 16, 2026

This test measures a protein called C-reactive protein (CRP) in your blood. CRP helps the body identify and respond to inflammation.

Quick summary

["CRP is a simple blood test to check for inflammation, often used to monitor conditions like infections or heart disease."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
101939-7
Short code
CND-DNA
Synonyms
C dubl+lusit+krus+auris DNA Spec Ql NAA
Category
chemistry
Sample
serum
Container
Serum separator tube (SST) or red-top vacutainer tube; sterile, leak-proof container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
CPT
87481
SNOMED
122450008
Specimen volume
1-2 mL serum (minimum 0.5 mL)
Stability
Room temperature: 24 hours; Refrigerated (2-8°C): 7 days; Frozen (-20°C or lower): 30 days. Avoid repeated freeze-thaw cycles.
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
24–72 hours
Order
routine

What Is CRP Used For?

CRP is primarily used to detect and monitor inflammation in the body. High levels may signal conditions such as infections, autoimmune diseases, or heart problems. Doctors may also use it to assess the risk of future heart events or to evaluate responses to treatments.

Why Might You Need This Test?

Your doctor may order this test if you have symptoms of inflammation, such as fever, swelling, or pain, or if you have a known condition that causes inflammation. It can also be part of routine check-ups for people at higher risk of heart disease or other inflammatory conditions.

What to Expect Before the Test

No special preparation is needed for this test. You may have a small needle inserted into a vein in your arm, and a small amount of blood will be drawn. This process usually takes a few minutes.

What Are the Possible Results?

Results are typically reported in milligrams per liter (mg/L). While reference ranges can vary by lab, higher than normal levels may indicate inflammation. Your doctor will interpret the results in the context of your overall health and medical history.

Reference range

Negative (Target Candida DNA not detected)N/A

Specimen: serum

No special preparation or fasting required. Specimen should be collected prior to initiation of antifungal therapy when possible, as antifungal agents may reduce pathogen DNA load and potentially yield false-negative results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

hs-CRP

Frequently asked questions

What Does a High CRP Level Mean?
A high CRP level often suggests inflammation in your body. This can be due to infections, injuries, autoimmune diseases, or other health conditions. It’s not specific to any one disease but can help guide treatment decisions.
What Does a Low CRP Level Mean?
A low CRP level usually means there is little to no inflammation in your body. However, it doesn’t rule out all causes of inflammation, so your doctor may still investigate further if needed.
How Often Should I Get This Test?
The frequency of this test depends on your health status and medical needs. Your doctor will determine how often you should have it based on your symptoms, diagnosis, or risk factors.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy