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Cefoxitin Minimum Inhibitory Concentration (MIC) by Broth Microdilution

Published: August 9, 2026Updated: August 16, 2026

This test measures how much of the antibiotic cefoxitin is needed to stop bacterial growth, helping doctors choose the best treatment for infections.

Quick summary

["Your doctor may use this test to pick the right antibiotic for bacterial infections."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
25220-5
Short code
CEFOX-SGM
Synonyms
cefOXitin Islt Slgr Mcbct AB 30.0
Category
chemistry
Sample
serum
Container
Sterile, leak-proof container; specify culture transport medium for mycobacterial specimens. Avoid formalin fixation.
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
≥ 0 years
Method
method-for-slow-growing-mycobacteria-antibiotic-concentration-at-ug-ml
CPT
87181
SNOMED
385719001
Specimen volume
Variable by specimen type: sputum 5-10 mL, BAL 10-30 mL, tissue as collected, blood 5-10 mL in SPS or ACD tube, CSF 1-2 mL minimum, urine 20-50 mL first morning void, sterile body fluids as available.
Stability
Refrigerate at 2-8°C; transport to laboratory within 24 hours of collection. For delayed processing, specimens may be refrigerated up to 7 days depending on specimen type. Do not freeze.
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
168–720 hours
Order
routine

What This Test Measures

The test uses a series of diluted cefoxitin solutions in a broth medium to determine the lowest concentration of the antibiotic that prevents bacterial growth. This helps identify the effectiveness of cefoxitin against specific bacteria in your sample.

Why It’s Done

Your healthcare provider may order this test if you have a suspected bacterial infection that might respond to cefoxitin, such as skin, joint, or bone infections. It’s often used when antibiotics are needed but the type of bacteria causing the infection isn’t known yet.

How the Test Works

A small sample of your blood or other bodily fluid is mixed with cefoxitin in a controlled environment. Bacteria are added to each well of a microdilution plate, and the test checks which concentration of cefoxitin stops bacterial growth after a set time.

What to Expect Before the Test

No special preparation is needed unless your doctor instructs you differently. You may be asked to avoid certain medications or foods that could affect test results, but this depends on the specific instructions given to you.

Reference range

Interpretive criteria: Susceptible (S), Intermediate (I), or Resistant (R) based on CLSI M24 guidelines for slow-growing mycobacteria. No quantitative reference range applies; results are reported categorically.N/A

Specimen: serum

No special patient preparation required. Specimen should be collected prior to initiation of anti-mycobacterial therapy when possible. For follow-up testing, note current medication regimen.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Cefoxitin MIC

Frequently asked questions

How does cefoxitin MIC help doctors treat infections?
The MIC result helps determine the minimum dose of cefoxitin needed to effectively treat your infection. A lower MIC means the bacteria are more sensitive to cefoxitin, and your doctor may prescribe it. A higher MIC suggests the bacteria may be resistant, and a different antibiotic might be needed.
What if my test shows cefoxitin is effective but I’m still not feeling better?
Even if cefoxitin is effective, some infections may take time to fully resolve. Follow your doctor’s treatment plan carefully, and let them know if symptoms persist or worsen. Additional testing or adjustments to your treatment may be needed.
Can I take cefoxitin if I’m allergic to other antibiotics?
If you have a known allergy to penicillin or other beta-lactam antibiotics, your doctor will carefully assess the risk versus benefit of cefoxitin. They may choose a different antibiotic or monitor you closely during treatment. Always discuss your full medical history with your doctor before starting any new medication.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy