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Cefoxitin Minimum Inhibitory Susceptibility (MIC) by Broth Microdilution

Published: August 9, 2026Updated: August 16, 2026

This test measures how much of the antibiotic cefoxitin is needed to stop bacterial growth, helping determine if bacteria are sensitive or resistant to this medication.

Quick summary

["Assists doctors in choosing the best antibiotic treatment for infections caused by bacteria."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
25366-6
Short code
CEFOX-SGM
Synonyms
cefOXitin Islt SlowMyco
Category
chemistry
Sample
serum
Container
Sterile, leak-proof, screw-cap container suitable for mycobacterial culture; for serum specimens, use serum separator tube (SST) or red-top tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
method-for-slow-growing-mycobacteria
CPT
87181
SNOMED
391902008
Specimen volume
Minimum 1-2 mL serum; for culture-derived isolates, provide sufficient pure growth material on solid or in liquid medium for inoculum preparation
Stability
Serum: stable for 24 hours at 2-8°C; freeze at -70°C for longer storage. Mycobacterial isolates should be tested promptly; refrigerate at 2-8°C if testing is delayed up to 48 hours.
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
168–720 hours
Order
routine

What This Test Measures

Cefoxitin is an antibiotic used to treat bacterial infections. The MIC test evaluates the lowest concentration of cefoxitin that prevents bacterial growth, indicating whether bacteria are likely to respond to this drug or develop resistance.

Why It Matters in Treatment

Results guide your healthcare provider in selecting the most effective antibiotic for your infection, reducing the risk of antibiotic resistance and improving treatment success.

Sample Collection and Preparation

A blood sample is collected and processed to isolate bacteria. The sample is then mixed with cefoxitin and bacterial growth is observed to determine the MIC value.

Common Uses and Indications

This test is typically performed on cultures of blood, joint fluid, or other body sites where bacterial infections are suspected, such as infections requiring surgery or severe systemic infections.

Reference range

Interpretive criteria per CLSI M24: Susceptible (S), Intermediate (I), or Resistant (R) based on minimum inhibitory concentration (MIC) breakpoints. For cefoxitin against Mycobacterium avium complex (MAC) and other slowly growing mycobacteria, consult current CLSI guidelines for organism-specific breakpoints.N/A

Specimen: serum

No special patient preparation required. Specimen should be collected prior to initiation of antimycobacterial therapy when clinically feasible. Avoid contamination during collection; use aseptic technique.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

MIC results help identify bacterial susceptibility patterns, ensuring targeted antibiotic therapy. Low MIC values suggest sensitivity, while high values indicate potential resistance, guiding appropriate treatment decisions.

Short name

MIC for Cefoxitin

Frequently asked questions

What does a low MIC value mean?
A low MIC value means the bacteria are likely to be sensitive to cefoxitin, and this antibiotic may be effective against the infection.
What does a high MIC value mean?
A high MIC value suggests the bacteria may be resistant to cefoxitin, and alternative antibiotics might be needed to treat the infection effectively.
How long does it take to get results from this test?
Results from this MIC test can take several days, as it involves culturing bacteria and observing growth patterns in the presence of cefoxitin.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy