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Concentration of cefuroxime in plasma (parenteral administration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of the antibiotic cefuroxime in your blood plasma after it has been given through an intravenous (IV) line.

Quick summary

["This test helps monitor how well your body is responding to cefuroxime treatment."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
146-1
Short code
CEFPAR
Synonyms
Cefuroxime Parenter Islt KB
Category
chemistry
Sample
serum
Container
Sterile transport container or culture transport system appropriate for specimen type (blood culture bottle, sterile urine container, swab in transport medium)
Units
N/A
Ref low
18
Fasting
false
Population
adult
Sex
all
Age range
≥ 0 years
Method
agar-diffusion
CPT
87181
SNOMED
405706009
Specimen volume
Variable depending on specimen type; minimum sufficient volume to perform isolation and susceptibility testing
Stability
Transport to laboratory as soon as possible; process within 2 hours for most specimens. Store at room temperature or as specified per specimen type requirements.
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
24–72 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you’re receiving cefuroxime, a type of antibiotic used to treat bacterial infections. Monitoring your cefuroxime levels helps ensure the medication is working effectively and helps prevent side effects or infections from developing resistance.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into a vein in your arm or hand for blood collection. The process usually takes a few minutes.

What the Test Results Mean

Results are used to guide dosing adjustments. If levels are too low, your provider may increase the dose. If levels are too high, they may adjust the treatment plan to avoid toxicity.

Possible Side Effects or Risks

While rare, high cefuroxime levels can sometimes cause allergic reactions or kidney issues. Your provider will watch for these and adjust your treatment accordingly.

Reference range

Interpretive categories per CLSI guidelines: Susceptible (S), Intermediate (I), Resistant (R), or Susceptible-Dose Dependent (SDD). Zone diameter breakpoints for cefuroxime parenteral: Susceptible >=18 mm, Intermediate 15-17 mm, Resistant <=14 mm.N/A

Specimen: serum

No special patient preparation required. Specimen should be collected prior to initiation of antimicrobial therapy when clinically feasible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Monitoring Antibiotics

Short name

Cefuroxime Plasma Level

Frequently asked questions

How often will I need this test?
Your provider will determine the frequency based on your treatment plan, typically during or shortly after starting IV cefuroxime, and then as needed for ongoing monitoring.
What if I miss a dose of cefuroxime?
If you miss a dose, contact your healthcare provider immediately. Skipping doses may reduce the effectiveness of the antibiotic or lead to resistance.
Can I drink alcohol while taking cefuroxime?
Alcohol can interfere with some antibiotics and may increase side effects. Avoid alcohol unless approved by your provider.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy