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Cefuroxime concentration in plasma (parenteral administration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of the antibiotic cefuroxime in your blood plasma after it has been given through an intravenous (IV) line. It helps doctors monitor how well your body is responding to this medication.

Quick summary

["This test helps track your treatment with cefuroxime, ensuring it stays at safe and effective levels."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
145-3
Short code
CEFPAR
Synonyms
Cefuroxime Parenter Islt MIC
Category
chemistry
Sample
serum
Container
Sterile transport container or blood culture bottle for sterile body fluids; sterile swab in transport medium for isolated organisms
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
Minimum Inhibitory Concentration (MIC) by broth microdilution or agar dilution per CLSI guidelines
CPT
87186
SNOMED
104206003
Specimen volume
Pure culture isolate on appropriate solid medium (e.g., Mueller-Hinton agar) or 1-2 mL of sterile body fluid
Stability
Pure cultures stable on appropriate media for up to 7 days at 2-8°C; clinical specimens should be processed within 2 hours of collection or refrigerated at 2-8°C for up to 24 hours
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
24–72 hours
Order
routine

Why This Test Is Done

Doctors may order this test if you’re receiving cefuroxime as part of a treatment plan, such as for bacterial infections. It helps them check whether the drug is working properly and adjust your dose if needed to avoid side effects or insufficient treatment.

What to Expect Before the Test

No special preparation is needed. You’ll have a blood sample drawn from a vein, usually in your arm, by a healthcare professional. The process is quick and typically painless, though you may feel a brief pinch.

What the Results Mean

Results provide a measurement of cefuroxime concentration in your plasma. While exact reference ranges vary by lab and patient factors, doctors use these results to guide treatment decisions, such as adjusting medication timing or dosage.

Possible Causes of Abnormal Results

Low levels might indicate the drug isn’t being absorbed well or is being processed too quickly by your body. High levels could suggest improper dosing or kidney issues affecting drug clearance.

Reference range

Interpretive categories: Susceptible (S) ≤8 mcg/mL, Intermediate (I) 16 mcg/mL, Resistant (R) ≥32 mcg/mL per CLSI breakpointsN/A

Specimen: serum

No special patient preparation required. Specimen should be collected prior to next antibiotic dose when possible for therapeutic drug monitoring correlation

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Cefuroxime Level (Plasma)

Frequently asked questions

What does a cefuroxime level tell me about my treatment?
Your doctor will use these results to ensure cefuroxime is at an effective concentration to fight infection without causing harmful side effects. They may adjust your treatment plan if levels are too low (infection may not be fully controlled) or too high (risk of toxicity).
How often will I need this test?
Frequency depends on your treatment plan. Some patients need monitoring daily or multiple times a week, while others may only need it periodically based on their condition and response to the drug.
What if my results are outside the expected range?
If results are abnormal, your doctor will review your medical history, current medications, and other test results to determine the cause. They may adjust your dose, change your treatment plan, or investigate other factors affecting your cefuroxime levels.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy