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Neutrophil count (absolute) in serum/plasma

Published: August 9, 2026Updated: August 15, 2026

This test measures the number of neutrophils, a type of white blood cell, in your blood. Neutrophils help fight infections.

Quick summary

["Neutrophils protect your body from bacterial infections; low or high levels may signal health concerns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 15, 2026Editorial policy

Key facts at a glance

LOINC
73040-8
Short code
CELX-NAb-IgG
Synonyms
Celecoxib (neut) IgG SerPl Ql FC
Category
chemistry
Sample
serum
Container
Serum separator tube (SST) or red-top tube for serum; EDTA or sodium heparin tube for plasma
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
flow-cytometry
CPT
86021 (Antibody identification; leukocyte antibody) or 86352 (Cellular function assay involving isolation and culture of lymphocytes) depending on laboratory billing practice
SNOMED
428368004 (Substance with neutrophil antibody) / 387458008 (Celecoxib-induced finding)
Specimen volume
2-5 mL of whole blood yielding at least 1 mL of serum or plasma
Stability
Serum/plasma stable for 24 hours at room temperature (15-25°C), 7 days at 2-8°C, and up to 6 months frozen at -20°C or below. Avoid repeated freeze-thaw cycles.
Hemolysis max
100
Lipemia max
100
Icterus max
50
TAT
48–120 hours
Order
routine

Why This Test Is Done

Your doctor may order this test to check for infections, blood disorders, or immune system issues. It can also help monitor conditions like leukemia, autoimmune diseases, or reactions to certain medications.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into your arm to draw blood. If you’re on blood thinners, let your doctor know before the test.

What the Results Mean

Results are typically reported as a count of neutrophils per microliter (cells/µL) of blood. While reference ranges vary by lab, very low counts (below normal) may indicate infections, immune disorders, or bone marrow problems. Very high counts may suggest infections, inflammation, or other conditions.

Common Conditions Monitored

This test is often used to diagnose or monitor conditions like severe infections, neutropenia (low neutrophil count), or to assess how your body responds to treatments like chemotherapy.

Reference range

Negative; IgG antibodies against neutrophils in the presence of celecoxib are not normally detected in healthy individualsN/A

Specimen: serum

No special preparation required. Patients should be informed that this test detects drug-dependent antibodies. Recent celecoxib exposure is relevant for accurate interpretation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Neutrophils Are Key Defenders

Short name

Absolute Neutrophil Count (ANC) Serum/Plasma

Frequently asked questions

What causes my neutrophil count to be different from what’s expected?
Several factors can affect neutrophil levels, including infections (like bacterial illnesses), inflammatory conditions, certain medications, or underlying blood disorders. If you’ve recently had an infection, taken antibiotics, or have a chronic condition, these may influence your results. Always discuss your full medical history with your doctor.
How long will it take to get my results?
Test results are usually available within 1–3 business days, depending on your lab. Your doctor will contact you once they have the results, but they may also provide a preliminary estimate during your visit.
Can I eat or drink before this test?
You can eat and drink normally before this test unless your doctor advises otherwise. No fasting is required for this blood draw.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy