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Lymphocyte Count (Blood)

Published: August 9, 2026Updated: August 16, 2026

This test measures the number of lymphocytes, a type of white blood cell that helps your immune system fight infections and diseases.

Quick summary

["Lymphocytes help protect your body by identifying and attacking harmful invaders like bacteria and viruses."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
107064-8
Short code
CD3T
Synonyms
Cells.CD3+CD19- (T cells)/lymph NFr Bld FC
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA) tube or specialized flow cytometry blood collection tube (e.g., BD Vacutainer CPT or ACD-A tube) per laboratory protocol
Units
N/A
Ref low
58
Ref high
84
Fasting
false
Population
adult
Sex
all
Age range
≥ 0 years
Method
flow-cytometry
CPT
86359
SNOMED
395130001
Specimen volume
3–5 mL of whole blood for adults; 1–3 mL for pediatric patients; minimum 1 mL
Stability
Specimen should be processed within 24–48 hours of collection when stored at room temperature (18–25°C). Refrigeration (2–8°C) may extend viability to 48 hours for some markers but can affect certain surface antigens; refer to laboratory-specific stability guidelines.
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What Are Lymphocytes?

Lymphocytes are a subset of white blood cells that play a crucial role in your immune response. They include B cells, T cells, and natural killer cells, each with specialized functions in defending your body against infections and preventing diseases like cancer.

Why Might You Need This Test?

Doctors may order a lymphocyte count to diagnose or monitor conditions such as infections, immune disorders (like lupus or rheumatoid arthritis), certain cancers (like leukemia), or to check how your immune system is responding to treatment.

How Is the Test Done?

A small amount of blood is drawn from a vein, usually in your arm. The sample is then analyzed in a lab to count the number of lymphocytes present in your blood.

What Do Results Mean?

Results are typically reported as a count per microliter (µL) of blood. Lower-than-normal counts may suggest immune deficiencies or infections, while higher-than-normal counts could indicate chronic inflammation, certain cancers, or autoimmune diseases.

Reference range

Adults: CD3+ T cells typically 58–84% of total lymphocytes (absolute count varies with total lymphocyte count). Pediatric reference ranges differ by age; consult age-specific reference table provided by the performing laboratory.N/A

Specimen: whole-blood

No fasting required. Patients should avoid recent corticosteroid or immunosuppressive therapy if possible, as these can transiently alter lymphocyte subset distributions. Inform the laboratory of any recent blood transfusions or immunomodulatory medications.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Lymphocyte Count

Frequently asked questions

Why do I need this test?
Your healthcare provider may recommend this test to assess your immune health, diagnose specific conditions, or evaluate how well your body is responding to treatment for diseases like cancer or autoimmune disorders.
What if my lymphocyte count is low?
A low lymphocyte count might mean you have a weakened immune system, which can increase your risk of infections. This could be due to conditions like HIV/AIDS, certain cancers, or medications that suppress the immune system.
How often should I get this test?
The frequency depends on your medical condition and treatment plan. Your doctor will determine how often you need this test based on your individual needs, such as monitoring chronic diseases or response to therapy.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy