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Lymphocyte Count in Blood (Absolute Count)

Published: August 9, 2026Updated: August 16, 2026

This test measures the number of lymphocytes, a type of white blood cell that helps your immune system fight infections and diseases.

Quick summary

["Lymphocytes are key to your body’s defense; abnormal counts may signal immune issues or other health concerns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
107062-2
Short code
BMCD3T
Synonyms
Cells.CD3+CD19- (T cells)/lymph NFr Mar FC
Category
chemistry
Sample
serum
Container
Heparinized (sodium or lithium heparin) sterile tube for bone marrow aspirate; EDTA tube acceptable for some flow cytometry platforms; transfer to flow cytometry lab in sterile condition
Units
N/A
Ref low
5
Ref high
20
Fasting
false
Population
adult
Sex
all
Age range
≥ 0 years
Method
flow-cytometry
CPT
86355
SNOMED
40970007
Specimen volume
1-3 mL of bone marrow aspirate in anticoagulant tube; minimum 0.5 mL acceptable for pediatric samples
Stability
Specimen should be processed within 24 hours of collection when stored at room temperature (18-25°C); may be refrigerated at 2-8°C for up to 48 hours if immediate processing is not feasible; viability decreases significantly beyond 48 hours
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–48 hours
Order
routine

Why It’s Done

Doctors may order this test to check for infections, autoimmune conditions, or other immune-related problems. It can also help monitor treatments for conditions like leukemia or HIV.

What to Expect

A simple blood draw is used. You’ll lie down while a healthcare provider inserts a needle into your arm. The blood is then sent to a lab for analysis.

Normal vs. Abnormal Results

While reference ranges vary by lab, lower-than-normal counts may indicate immune suppression, while higher-than-normal counts could suggest chronic infections or certain cancers.

Common Conditions

Lymphocyte counts are often checked in people with weakened immune systems, those recovering from illness, or those undergoing cancer treatment.

Reference range

Reference ranges for bone marrow T cell (CD3+CD19-) subsets vary by age. Adult bone marrow typically shows T cells comprising 5-20% of lymphocytes. Pediatric values may differ. Always interpret in conjunction with concurrent bone marrow morphological and immunophenotypic assessment.N/A

Specimen: serum

No special patient preparation required. Recent transfusion, immunosuppressive therapy, or chemotherapy may affect results and should be documented. Bone marrow aspiration procedure requires standard informed consent and local anesthesia.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Lymphocytes play a critical role in immune response. Low counts may reflect conditions like HIV/AIDS, certain cancers, or severe infections, while elevated counts can signal chronic inflammation, autoimmune disorders, or reactive immune responses.

Short name

Lymphocyte Count

Frequently asked questions

What causes a low lymphocyte count?
Low lymphocyte counts can result from infections (like HIV), certain medications, autoimmune diseases, or conditions that weaken the immune system, such as chemotherapy or radiation therapy.
What causes a high lymphocyte count?
High lymphocyte counts may occur with chronic infections (e.g., tuberculosis), certain cancers (e.g., lymphoma), or autoimmune diseases like rheumatoid arthritis.
How often should I get this test?
Your doctor will determine how often you need this test based on your health condition, treatment plan, or symptoms. Regular monitoring may be needed if you have an ongoing immune-related illness.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy