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Cell Count in Cerebrospinal Fluid (CSF)

Published: August 9, 2026Updated: August 16, 2026

This test measures the number of cells present in your cerebrospinal fluid, which is the fluid surrounding your brain and spinal cord. It helps assess conditions affecting the central nervous system.

Quick summary

["A CSF cell count helps diagnose or monitor neurological conditions by checking for abnormal cell presence."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
64089-6
Short code
Cells counted CVS
Synonyms
Cells counted CVS
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
molgen
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order a CSF cell count to investigate symptoms like headaches, neck stiffness, confusion, or neurological issues. It can also be used to monitor conditions such as infections (e.g., meningitis), inflammation, or blood leaks into the CSF.

What to Expect Before the Test

You’ll likely undergo a lumbar puncture (spinal tap) where a small needle is inserted into your lower back to collect CSF. The procedure is usually quick but may cause mild discomfort. No special preparation is needed, but inform your doctor about any medications or allergies.

What Happens During the Test?

After the needle is inserted, a small amount of CSF is drawn into a tube. The sample is then sent to a lab for cell counting. The test itself is painless, but you may feel pressure or a slight sting during the procedure.

What Are Possible Results?

Results show the total number of cells (white blood cells, red blood cells, and sometimes other cells) in the CSF. Abnormal counts may indicate infections, bleeding, or other neurological issues.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A normal CSF cell count typically ranges between 0–5 white blood cells per microliter. Elevated counts (especially white blood cells) may signal infections like meningitis, while abnormal red blood cell counts could indicate bleeding or trauma. Your doctor will interpret results in the context of your symptoms and medical history.

Short name

CSF Cell Count

Frequently asked questions

How long does it take to get the results of this test?
Results are usually available within 1–2 business days, depending on lab processing times. Your doctor will contact you once they have the findings.
What does a high or low cell count mean?
A high cell count (especially white blood cells) often suggests inflammation, infection, or other neurological problems. A low count is usually normal, but repeated tests may be needed if symptoms persist. Your doctor will discuss findings with you.
Can I eat or drink before this test?
You can eat and drink normally before the test unless instructed otherwise. Avoid caffeine or heavy meals if your doctor specifies, as they may affect the procedure.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy