C-reactive protein (CRP) with high-sensitivity measurement
This test measures a protein produced by the liver in response to inflammation, often used to monitor low-level inflammation in the body.
["Helps detect subtle signs of inflammation that may not be obvious otherwise."]
Key facts at a glance
- LOINC
- 106507-7
- Short code
- CALEV
- Synonyms
- CEV IgG+IgM CSF IF-Imp
- Category
- chemistry
- Sample
- csf
- Container
- Sterile CSF collection tube (polypropylene)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- Immunofluorescence (IFA)
- CPT
- 86651
- SNOMED
- 395130008
- Specimen volume
- 1-2 mL of cerebrospinal fluid
- Stability
- Refrigerated at 2-8°C for up to 7 days; frozen at -20°C or below for longer storage. Avoid repeated freeze-thaw cycles.
- Hemolysis max
- 200
- TAT
- 24–72 hours
- Order
- routine
What Is High-Sensitivity CRP Used For?
High-sensitivity CRP (hs-CRP) is primarily used to assess the risk of future heart disease or inflammation-related conditions. It can help doctors evaluate whether you have low-grade inflammation that might contribute to conditions like atherosclerosis or other chronic diseases.
How Is the Test Performed?
A small blood sample is drawn from a vein, usually in your arm. The blood is then processed to measure the hs-CRP level. This test is typically done using a blood sample taken from your arm, similar to other routine blood tests.
Why Might Your Doctor Order This Test?
Your doctor may recommend hs-CRP testing if you have risk factors for heart disease, such as high cholesterol, high blood pressure, diabetes, or a family history of heart problems. It may also be used to monitor chronic conditions like rheumatoid arthritis or other inflammatory diseases.
What Does a High or Low Result Mean?
Results are not interpreted in absolute terms alone but are often used alongside other clinical factors. High levels of hs-CRP may indicate increased inflammation, which could be linked to higher cardiovascular risk. Low levels suggest minimal inflammation.
Reference range
Negative: No IgG or IgM antibodies detected against California encephalitis virus. Positive: IgG and/or IgM antibodies detected, suggestive of past exposure or acute infection respectively.N/A
No special patient preparation required. Lumbar puncture should be performed under sterile conditions by qualified personnel.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance: hs-CRP as a Marker for Inflammation and Cardiovascular Risk
Short name
hs-CRP (high-sensitivity C-reactive protein)
Frequently asked questions
Why do some people experience false results or variability in hs-CRP levels?
How soon after a procedure or illness should I expect my hs-CRP levels to return to normal?
Can lifestyle changes affect hs-CRP levels?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy