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Serum Creatinine Concentration (Mass Concentration)

Published: August 9, 2026Updated: August 15, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood. It helps assess how well your kidneys are filtering blood.

Quick summary

["A creatinine test helps check kidney function by measuring waste in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 15, 2026Editorial policy

Key facts at a glance

LOINC
35694-9
Short code
CALENCIGG
Synonyms
CEV IgG Titr Ser
Category
chemistry
Sample
serum
Container
Serum separator tube (SST) or red-top vacutainer tube
Units
N/A
Ref low
0
Ref high
1
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
Enzyme-Linked Immunosorbent Assay (ELISA) or Immunofluorescence Assay (IFA) for detection of IgG antibodies
CPT
86651
SNOMED
39508007
Specimen volume
1-2 mL of serum
Stability
Stable for 7 days at 2-8°C; for longer storage, freeze at -20°C or below. Avoid repeated freeze-thaw cycles.
Hemolysis max
100
Lipemia max
50
Icterus max
20
TAT
48–168 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test to monitor kidney health, especially if you have symptoms like swelling, fatigue, or changes in urine output. It’s also used before certain procedures, during pregnancy, or if you have conditions like diabetes or high blood pressure that can affect kidney function.

What to Expect Before the Test

No special preparation is needed unless instructed. You may drink water as usual, but avoid alcohol before testing. If you’re on a low-protein diet, follow your doctor’s advice.

What Happens During the Test?

A small blood sample is drawn from a vein, usually in your arm. It only takes a few minutes, and you may feel a slight pinch. The sample is sent to a lab for analysis.

What the Results Mean

Higher than expected levels may signal kidney problems, while lower levels could indicate muscle breakdown or other conditions. Your doctor will interpret results in relation to your overall health.

Reference range

Titer <1:10 or negative: No detectable IgG antibodies; Titer >=1:10 suggests past exposure or past infection. A fourfold or greater rise in titer between acute and convalescent specimens indicates recent infection.N/A

Specimen: serum

No special patient preparation required. Fasting is not necessary.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Serum Creatinine

Frequently asked questions

What causes creatinine levels to be too high?
High creatinine levels can result from reduced kidney function, dehydration, severe muscle damage, or certain medications. Chronic kidney disease, diabetes, or heart failure may also contribute.
How often should I get this test?
Your doctor will determine how often you need this test based on your health status. Regular monitoring may be recommended if you have kidney-related conditions or risk factors.
Can diet affect creatinine levels?
Dietary protein intake can influence creatinine levels, but the effect is usually small. Avoiding excessive protein may help if your kidneys are struggling, but always follow your doctor’s guidance.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy