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Serum Creatinine Concentration (Mass Concentration)

Published: August 9, 2026Updated: August 15, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood. It helps assess how well your kidneys are filtering blood.

Quick summary

["Creatinine levels help check kidney function and detect early kidney problems."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 15, 2026Editorial policy

Key facts at a glance

LOINC
49140-7
Short code
CALEVG
Synonyms
CEV IgG Titr Ser IF
Category
chemistry
Sample
serum
Container
Red-top serum tube or serum separator tube (SST)
Units
N/A
Ref low
0
Ref high
1
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
Immunofluorescence (IFA)
CPT
86651
SNOMED
40668006
Specimen volume
1.0 mL serum (minimum 0.5 mL)
Stability
Stable at 2-8°C for 7 days; frozen at -20°C or below for long-term storage up to 1 year; avoid repeated freeze-thaw cycles
Hemolysis max
100
Lipemia max
50
Icterus max
20
TAT
24–96 hours
Order
routine

Why This Test Matters

Creatinine is a byproduct of muscle breakdown and is normally filtered out by your kidneys. High levels may indicate reduced kidney function, while low levels could suggest dehydration or muscle loss. This test is often used alongside other measures, like blood urea nitrogen (BUN), to evaluate kidney health.

What to Expect Before the Test

No special preparation is needed for this blood test. You may have a small needle inserted into your arm to draw a blood sample. If you’re dehydrated, your doctor might advise drinking extra fluids the day before.

Common Causes of Abnormal Results

High creatinine levels might be due to kidney disease, dehydration, or conditions that increase muscle breakdown (e.g., severe illness). Low levels could result from dehydration, low muscle mass, or certain medications. Always discuss symptoms with your healthcare provider.

What Your Results Mean

Your results will be compared to standard ranges for your age, sex, and overall health. Your doctor will interpret them in the context of your medical history and other tests. If results are outside normal limits, further evaluation may be needed.

Reference range

Negative: <1:10; Positive: ≥1:10 indicates previous exposure or past infection with California encephalitis virus (La Crosse virus). Seroconversion or a four-fold rise in titer between acute and convalescent samples indicates recent or current infection.N/A

Specimen: serum

No fasting or special preparation required. Acute and convalescent serum samples collected 2-4 weeks apart are recommended for accurate serological diagnosis. Patient should be informed that the test detects antibodies to California encephalitis virus, a mosquito-borne arbovirus that can cause encephalitis, particularly in children.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Creatinine

Frequently asked questions

How often should I get this test?
Your doctor will determine how often you need this test based on your health status. For example, people with kidney disease may need it more frequently, while others with no known issues might only need it occasionally.
Can I eat or drink before this test?
You can eat and drink normally before this test unless your doctor instructs otherwise. Avoiding fluids the day before may not be necessary unless you’re scheduled for another test that requires fasting.
What if my results are different from last time?
Changes in creatinine levels can be influenced by factors like diet, hydration, muscle activity, or underlying health changes. Always talk to your doctor about any differences, as they may need further investigation.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy