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Antibody Detection to Amatoxins (e.g., *Amanita* toxins) in Whole Blood

Published: August 9, 2026Updated: August 16, 2026

This test checks for antibodies in your blood that may indicate exposure to toxins from certain mushrooms, such as those in the *Amanita* genus (e.g., fly agaric). Antibodies suggest your body has recognized these toxins, which can be harmful if ingested.

Quick summary

["Detects potential mushroom poisoning exposure through immune system response."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
92793-9
Short code
CFAMNAA
Synonyms
C famata DNA Bld Pos Ql NAA+probe
Category
chemistry
Sample
whole-blood
Container
Positive blood culture bottle (aerobic or anaerobic) confirmed as positive by continuous monitoring blood culture system
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
CPT
87149
SNOMED
122451000119108
Specimen volume
1-2 mL aliquot taken from positive blood culture broth for molecular testing
Stability
Blood culture broth: stable at room temperature or 35-37°C until flagged positive; post-positive, process within 24 hours; extracted nucleic acid stable at 2-8°C for up to 48 hours or -70°C for long-term storage
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
2–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you or someone you know has consumed mushrooms from the *Amanita* genus, experienced symptoms like nausea, vomiting, or abdominal pain shortly afterward, or if you live in an area where toxic mushrooms grow. It can also be used in cases of suspected poisoning to assess immune response.

What to Expect Before the Test

No special preparation is needed. You’ll provide a small sample of whole blood drawn from a vein, similar to other blood tests. The sample is sent to a lab for analysis.

What the Results Mean

Positive results indicate your immune system has detected amatoxin-related antibodies, which may suggest exposure. However, antibodies alone don’t confirm poisoning—other tests or clinical symptoms are needed for diagnosis. Negative results mean no detectable antibodies were found in this sample.

What Happens Next

If results are positive, your provider may recommend further evaluation, including symptoms monitoring, additional tests, or medical treatment if poisoning is suspected. Follow-up may depend on your symptoms and medical history.

Reference range

Negative (Candida famata DNA not detected)N/A

Specimen: whole-blood

No special patient preparation required. Specimen is collected as part of standard blood culture collection when sepsis or bloodstream infection is suspected.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Amanita Toxin Antibody Test (bld)

Frequently asked questions

How long does it take to get results from this test?
Results are typically available within 1–3 business days, depending on lab processing times. Your healthcare provider will contact you with the outcome once complete.
Can I eat or drink anything before this blood test?
No restrictions apply. You can eat, drink water, or take medications as usual. The blood draw is quick and doesn’t require fasting.
What are the most common symptoms of *Amanita* mushroom poisoning?
Common symptoms include severe vomiting, diarrhea, abdominal pain, sweating, and confusion. In severe cases, symptoms may progress to liver or kidney failure. Seek emergency care immediately if you or someone else experiences these symptoms after consuming suspicious mushrooms.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy