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C-reactive protein (CRP) with high-sensitivity measurement by turbidimetry

Published: August 9, 2026Updated: August 16, 2026

This test measures a protein produced by your body in response to inflammation, helping assess low-level inflammation or infection.

Quick summary

["High-sensitivity CRP helps track subtle inflammatory activity that may not be detected by other tests."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
103169-9
Short code
CFREUND
Synonyms
C freundii DNA Wnd Ql NAA+probe
Category
chemistry
Sample
serum
Container
Sterile, leak-proof container or swab transport system (e.g., ESwab, Copan swab, or sterile saline for tissue/aspirate)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
0–120 years
Method
probe-amp-tar
CPT
87798
SNOMED
122456007
Specimen volume
1-3 mL of wound exudate, aspirate, or tissue biopsy; swab specimens collected per device manufacturer guidelines
Stability
Room temperature: 24 hours; Refrigerated (2-8°C): 7 days; Frozen (-70°C or below): 30 days. Transport to laboratory as soon as possible to preserve nucleic acid integrity.
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
24–72 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test to monitor chronic conditions like heart disease, arthritis, or autoimmune disorders, or to check for signs of infection or inflammation before surgery or other procedures.

What Does the Result Mean?

Results are not provided as a single numeric range since reference intervals vary by lab and patient factors. Elevated levels may indicate inflammation, infection, or other health concerns requiring further evaluation.

What to Expect Before the Test

No special preparation is needed. You may eat and drink normally. If you’re taking blood, a healthcare provider will explain the process and any precautions.

What to Expect During the Test

Blood is drawn from a vein in your arm. You may feel a slight pinch, but it usually takes only a few minutes. You can resume normal activities afterward.

Reference range

Negative (Not Detected) for Citrobacter freundii DNAN/A

Specimen: serum

No fasting required. Avoid contaminating the wound sample with skin flora prior to collection. Discontinue topical antibiotics or antiseptic dressings at least 24 hours before specimen collection if clinically feasible. Inform the laboratory of any recent antimicrobial therapy.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Inflammation and Risk Assessment

Short name

hs-CRP

Frequently asked questions

What does a high or low CRP level mean?
Elevated CRP levels often signal inflammation, which can be linked to infections, autoimmune diseases, or other health issues. Low levels may suggest reduced inflammation, but they don’t always mean you’re healthy. Your doctor will interpret results in the context of your medical history and other tests.
Can CRP levels change over time?
Yes, CRP levels can fluctuate due to illness, stress, recent injury, or medications. Regular monitoring may be needed for conditions like heart disease or arthritis to track trends.
Is fasting required for this test?
No, fasting is not required. Blood is typically drawn at any time of day, though results may be affected by recent meals or medications.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy