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C-reactive protein (CRP) by nephelometry (serum/plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures a protein called C-reactive protein (CRP), which your body produces in response to inflammation. It helps doctors assess whether you have low-grade inflammation that might be linked to conditions like heart disease or autoimmune disorders.

Quick summary

CRP helps track subtle inflammation, often used alongside other tests for early risk assessment.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
105804-9
Short code
C gattii+neofor DNA Ct Bld + Qn NAA+pr
Synonyms
C gattii+neofor DNA Ct Bld + Qn NAA+pr
Category
coagulation
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why CRP Matters in Your Health

CRP is a marker for inflammation, a natural response your body uses to fight infections or injury. While CRP levels rise with infections, injuries, or surgeries, they can also be elevated in conditions like arthritis, heart disease, or certain cancers. High sensitivity CRP is particularly useful for detecting low-level inflammation that might not be obvious otherwise.

How This Test Works

Your blood sample is analyzed using nephelometry, a method that measures how much light is scattered by CRP particles in your serum or plasma. This helps determine the precise concentration of CRP in your blood.

What to Expect Before the Test

No special preparation is needed for this test. You may have a small needle inserted into your arm to draw blood, similar to other routine blood tests. If you’re on blood thinners, let your healthcare provider know before the test.

Common Reasons for Testing

Doctors may order CRP testing to monitor chronic conditions like rheumatoid arthritis, check for signs of heart disease risk, evaluate symptoms of infection, or assess inflammation after surgery or injury.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated CRP levels can signal inflammation, which may indicate underlying health concerns such as cardiovascular disease, autoimmune disorders, or infections. High sensitivity CRP is particularly useful for early detection of inflammation that might not be detected by standard tests. However, CRP alone isn’t diagnostic—it’s often used alongside other tests and clinical findings to guide treatment decisions.

Short name

CRP (High Sensitivity)

Frequently asked questions

How often should I get this test?
The frequency depends on your health condition and why your doctor ordered it. For example, people with heart disease or autoimmune disorders might get CRP tests every few months or annually. Always follow your healthcare provider’s recommendations.
Does CRP test show if I have an infection?
CRP can rise with infections, but it’s not specific to them. It may also increase with other inflammatory conditions. If you suspect an infection, your doctor may order additional tests like blood cultures or other diagnostic tools.
Can diet or exercise affect CRP levels?
Yes, lifestyle factors like diet, exercise, and weight can influence CRP levels. Eating a heart-healthy diet, staying active, and maintaining a healthy weight may help lower CRP and reduce inflammation over time.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy