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Antibody Screening for Antibodies to Hepatitis B Surface Antigen (IgG)

Published: August 9, 2026Updated: August 16, 2026

This test checks for antibodies to the hepatitis B virus surface antigen, which can indicate past or current exposure to hepatitis B. It helps determine if you’ve been vaccinated, naturally infected, or if the virus is still active.

Quick summary

["This screening helps assess immunity and infection status from hepatitis B exposure."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
85782-1
Short code
CGLDNA
Synonyms
C glabrata DNA Bld Pos Ql NAA+n-prb
Category
chemistry
Sample
whole-blood
Container
Positive blood culture bottle (aerobic or anaerobic) submitted for testing; transfer to sterile molecular testing container may be required
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
0–120 years
Method
non-probe-amp-tar
CPT
87481
SNOMED
122451000146107
Specimen volume
1-2 mL aliquot from positive blood culture bottle or per laboratory-specific protocol
Stability
Blood culture bottles: stable per blood culture system specifications (typically up to 5 days). Once removed from bottle, process immediately or refrigerate at 2-8°C for up to 24 hours. For prolonged delays, freeze at -70°C or below.
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
2–24 hours
Order
routine

Why This Test Matters

Hepatitis B is a serious liver infection caused by the hepatitis B virus (HBV). Antibodies to the hepatitis B surface antigen (HBsAb) can appear after vaccination or infection. This test helps doctors track immunity, diagnose past infections, or confirm vaccination success.

What to Expect Before the Test

You may have a simple blood draw from a vein in your arm. No special preparation is needed, but inform your doctor if you’re pregnant, have bleeding issues, or take blood thinners.

What the Results Mean

Positive results suggest immunity (either from vaccination or prior infection). Negative results mean no detectable antibodies, which may require further testing or booster evaluation.

Common Reasons for Testing

Doctors may order this test for newborns to check for maternal infection, before vaccination, during travel to high-risk areas, or if you’ve had unprotected sex with someone infected.

Reference range

Negative for Candida glabrata DNA. A positive result indicates the presence of Candida glabrata DNA in the positive blood culture.N/A

Specimen: whole-blood

No special patient preparation required. Specimen is collected from a positive blood culture bottle, not directly from the patient.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test is critical for preventing hepatitis B spread. It helps identify high-risk individuals, guides vaccination decisions, and supports monitoring of chronic infection. Early detection allows for timely treatment and prevention of liver damage.

Short name

Hepatitis B Surface Antibody Screen (IgG)

Frequently asked questions

What does a positive result mean?
A positive result means your body has produced antibodies to the hepatitis B surface antigen, indicating either prior vaccination or natural immunity from infection. This does not mean you’re currently infected but confirms protection.
Do I need to fast before this test?
No fasting is required. Blood tests like this are typically done on an empty stomach, but you can eat lightly if needed. Always follow your healthcare provider’s instructions.
How long does it take to get results?
Results are usually available within 1–3 business days, depending on your lab. Your doctor will discuss them with you during your follow-up visit.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy