Guillain-Barré Syndrome Antibody Profile (IgG) - Serum
This test measures antibodies in your blood that may be linked to Guillain-Barré Syndrome, a rare but serious condition causing muscle weakness and nerve damage. It helps doctors assess potential immune-related causes of your symptoms.
["This test can help identify if your immune system is producing antibodies against nerve proteins, which may be linked to Guillain-Barré Syndrome or other autoimmune conditions."]
Key facts at a glance
- LOINC
- 101781-3
- Short code
- CANDGUI
- Synonyms
- C guilliermondii DNA Spec Ql NAA+probe
- Category
- chemistry
- Sample
- serum
- Container
- Sterile, screw-capped, leak-proof collection tube or dedicated fungal/molecular transport device; serum separator tube (SST) acceptable for serum specimens
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 0–120 years
- Method
- probe-amp-tar
- CPT
- 87801 (Infectious agent detection by nucleic acid, multiple organisms; amplified probe technique) or 87481 (single organism)
- SNOMED
- 122446006 | Candida guilliermondii (organism)
- Specimen volume
- 1-2 mL serum
- Stability
- Room temperature: 24 hours; Refrigerated (2-8°C): 7 days; Frozen (-20°C or lower): 30 days. Avoid repeated freeze-thaw cycles.
- Hemolysis max
- 100
- Lipemia max
- 100
- Icterus max
- 40
- TAT
- 24–72 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms like sudden weakness, numbness, or difficulty moving—especially after a recent infection. It’s also used to monitor patients with suspected Guillain-Barré Syndrome or other autoimmune nerve disorders.
What to Expect Before the Test
No special preparation is needed. You’ll provide a blood sample, usually drawn from your arm. The test involves a small needle, and you may feel a brief pinch. If you’re nervous, let your provider know so they can offer comfort measures.
What the Test Results Mean
Results are qualitative (positive/negative) rather than numeric. A positive result means your blood contains antibodies against specific nerve proteins, which may indicate an autoimmune response. This doesn’t confirm Guillain-Barré Syndrome alone but supports further evaluation.
Common Reasons for Testing
Doctors use this test to rule out or confirm Guillain-Barré Syndrome, diagnose autoimmune nerve disorders, or assess immune-related nerve damage in other conditions like chronic inflammatory demyelinating polyneuropathy (CIDP).
Reference range
Negative (Target DNA not detected)N/A
No fasting required. Specimen should be collected prior to initiation of antifungal therapy when possible, as antimicrobial agents may affect detection. Inform the laboratory of any recent antimicrobial treatment.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance: Understanding the Role of Antibodies
Short name
Guillain-Barré Antibody Screen
Frequently asked questions
What symptoms might trigger this test?
How long does it take to get results?
Can this test be done at home?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy