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Cholesterol Mass Concentration in Serum (Total Cholesterol)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of cholesterol in your blood serum. Cholesterol is a type of fat your body needs for healthy cells, but too much can raise your risk of heart disease.

Quick summary

["Your total cholesterol level helps assess heart health risk—aim for balanced levels with guidance from your healthcare provider."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
76141-1
Short code
CHCMr Bld-mCnc
Synonyms
CHCMr Bld-mCnc
Category
hematology
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What Cholesterol Is and Its Role in Your Body

Cholesterol is a waxy substance found in your blood, produced by your liver and also obtained from foods like eggs, fatty meats, and dairy. It’s essential for building cell membranes and producing hormones, but too much cholesterol can build up in your arteries, increasing the risk of heart disease or stroke.

Why This Test Matters for Your Health

High cholesterol levels often don’t cause symptoms, so regular testing is key. Your doctor may recommend this test if you have a family history of heart disease, high blood pressure, diabetes, or other risk factors.

How the Test Works

A small blood sample is drawn from your arm. The serum (liquid part of blood after clotting) is then analyzed to measure total cholesterol concentration using a reliable laboratory method.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast (not eat or drink) for 12 hours before the test if your doctor recommends it. Wear comfortable clothing and plan for a short visit to the lab.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Total Cholesterol

Frequently asked questions

What does a high or low total cholesterol level mean?
High total cholesterol (above recommended levels) increases the risk of plaque buildup in your arteries, which can lead to heart disease or stroke. Low levels may indicate other health concerns, like liver disease or malabsorption issues, but results should always be interpreted by your healthcare provider.
How often should I get this test?
Your doctor will determine how often you need this test based on your age, medical history, and risk factors. Typically, adults with no risk factors may get it every 4–6 years, while those with risk factors may need it more frequently.
Can lifestyle changes affect my cholesterol levels?
Yes! Eating a balanced diet low in saturated and trans fats, exercising regularly, maintaining a healthy weight, and avoiding smoking can help improve cholesterol levels naturally. Always follow your doctor’s advice for personalized recommendations.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy