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Serum or Plasma Creatinine Concentration (Mass Concentration)

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood. It helps assess how well your kidneys are filtering blood.

Quick summary

["A key measure of kidney function and overall kidney health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
100421-7
Short code
CHKPIGG
Synonyms
Chickpea IgG Qn
Category
chemistry
Sample
serum
Container
Serum separator tube (SST) or red-top vacutainer tube
Units
N/A
Ref low
22
Ref high
198
Critical range
— – 10000 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
Immunoassay (Enzyme-Linked Immunosorbent Assay, ELISA)
CPT
86001
SNOMED
395790006
Specimen volume
1-2 mL of serum
Stability
Stable for 7 days at 2-8°C. For longer storage, freeze at -20°C or below for up to 6 months. Avoid repeated freeze-thaw cycles.
Hemolysis max
100
Lipemia max
100
Icterus max
50
TAT
24–72 hours
Order
routine

Why This Test Matters

Creatinine levels can indicate how well your kidneys are working. High levels may suggest kidney problems, while low levels could indicate dehydration or other conditions. Your doctor may order this test to monitor kidney function, especially if you have conditions like diabetes, high blood pressure, or a history of kidney disease.

What to Expect Before the Test

No special preparation is needed for this blood test. You may have a small needle inserted into your arm to draw a blood sample. If you’re on a low-protein diet or have recently exercised, your levels might be temporarily affected, but this is usually normal.

Possible Results and What They Mean

Results are typically reported in milligrams per deciliter (mg/dL) or millimoles per liter (mmol/L). While reference ranges vary by lab, higher than expected levels may signal kidney issues, while very low levels might raise concerns about hydration or muscle breakdown.

Common Conditions Affecting Results

Several factors can influence creatinine levels, including muscle mass, diet, hydration status, and certain medications. Conditions like kidney disease, heart failure, or severe dehydration can lead to elevated levels, while muscle disorders or excessive fluid intake may lower them.

Reference range

Adult males: 22-198 U/L; Females: 22-198 U/LN/A

Specimen: serum

No special preparation required. Patient does not need to fast prior to sample collection. It is recommended to avoid taking antihistamines for several days before testing if clinically feasible, as they may affect interpretation of allergy panels. Patients should maintain their normal diet, and recent chickpea ingestion does not interfere with IgG antibody detection.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Creatinine

Frequently asked questions

What causes creatinine levels to be abnormal?
Abnormally high creatinine levels often point to reduced kidney function, but they can also result from dehydration, high muscle activity, or certain medications. Abnormally low levels may suggest dehydration, muscle wasting, or conditions like liver disease that affect protein metabolism.
How often should I get this test?
Your doctor will determine how often you need this test based on your health history, current conditions, and overall kidney function. Regular monitoring may be recommended if you have kidney disease, diabetes, or high blood pressure.
Can diet or exercise affect my creatinine levels?
Yes, diet (especially protein intake) and exercise can influence creatinine levels. Eating a high-protein diet or intense exercise may temporarily raise levels, while dehydration can also affect them. Always follow your doctor’s advice regarding diet and activity levels before testing.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy