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Chikungunya Virus IgG Antibody, Serum (Quantitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of antibodies in your blood that your immune system produces in response to a chikungunya virus infection. Antibodies help your body fight off infections.

Quick summary

["Detects past exposure to chikungunya virus through antibody presence."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
104364-5
Short code
CHIKVIGG
Synonyms
CHIKV IgG sp1 Titr Ser IA
Category
chemistry
Sample
serum
Container
Serum separator tube (SST) or red-top tube
Units
N/A
Ref low
2
Ref high
4
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
Immunoassay (Enzyme-linked immunosorbent assay/ELISA)
CPT
86790
SNOMED
122450005
Specimen volume
1-2 mL of serum
Stability
Serum stable for 7 days at 2-8°C; for longer storage, freeze at -20°C or below. Avoid repeated freeze-thaw cycles.
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
24–72 hours
Order
routine

What Does This Test Measure?

The test looks for IgG antibodies specific to chikungunya virus. IgG antibodies are a type of immune protein that your body makes after recovering from an infection or after vaccination. They provide long-term immunity. This test is used to confirm past exposure to the virus, not to diagnose an active infection.

Why Might You Need This Test?

A chikungunya virus IgG antibody test may be recommended if you have symptoms like joint pain, fever, or rash that suggest chikungunya infection, especially if you traveled to or lived in an area where the virus is common. It can help determine if you’ve had the virus before, which may be important for future health decisions or travel planning.

How Is the Test Performed?

A blood sample is taken from a vein in your arm. The sample is sent to a lab where it is tested for the presence of IgG antibodies using a sensitive immunoassay method. The lab will analyze the sample to determine antibody levels.

What Are the Results?

Results are reported as either positive or negative for IgG antibodies. A positive result means your body has produced antibodies against chikungunya virus, indicating past infection. A negative result means no detectable antibodies were found at the time of testing.

Reference range

Negative: <1:10 titer; Positive: ≥1:10 titer. A four-fold rise in titer between acute (1st specimen) and convalescent (2nd specimen) specimens collected 2-4 weeks apart is considered diagnostically significant.N/A

Specimen: serum

No special patient preparation required. Specimen should be collected as the acute phase (1st specimen) ideally within the first week of symptom onset for optimal paired serology interpretation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A positive IgG antibody test confirms that you have been exposed to chikungunya virus at some point. This can be useful for understanding your immune response, planning future travel to endemic regions, or assessing risk for future infections. It does not indicate whether you currently have an active infection, as IgG antibodies develop after recovery. If you suspect an active infection, other diagnostic tests may be needed.

Short name

IgG Antibody to Chikungunya Virus

Frequently asked questions

What Does a Positive Result Mean?
A positive result means your immune system has recognized and fought off chikungunya virus in the past. This does not mean you are currently infected, but it confirms past exposure. You may have developed immunity, though this can vary.
What If My Test Result Is Negative?
A negative result means no detectable IgG antibodies were found at the time of testing. This could mean you have never been exposed to chikungunya virus, or it may be too early in your infection for antibodies to develop. If you suspect you’ve been exposed, follow up with your healthcare provider.
How Long Do IgG Antibodies Last?
IgG antibodies to chikungunya virus typically remain in your blood for months to years after infection. However, their exact duration can vary. If you plan to travel to areas where chikungunya is common, discuss your test results with your doctor to determine if additional testing or precautions are needed.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy