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Vitamin D Binding Protein (DBP) – Serum Concentration

Published: August 9, 2026Updated: August 15, 2026

This test measures the level of vitamin D binding protein in your blood, which helps transport vitamin D and other hormones.

Quick summary

["Vitamin D binding protein supports hormone transport and may influence vitamin D metabolism."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 15, 2026Editorial policy

Key facts at a glance

LOINC
56130-8
Short code
CHIKV IGM
Synonyms
CHIKV IgM Titr SerPl IF
Category
chemistry
Sample
serum
Container
Serum separator tube (SST) or red-top tube (no anticoagulant); plasma collected in EDTA or heparin tubes is also acceptable
Units
N/A
Ref low
0
Ref high
1
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
Immunofluorescence Assay (IFA)
CPT
86790
SNOMED
122620004
Specimen volume
1-2 mL of serum or plasma (minimum 0.5 mL)
Stability
Serum or plasma stable for 7 days at 2-8°C; for longer storage, freeze at -20°C or below for up to 30 days. Avoid repeated freeze-thaw cycles. Hemolyzed, lipemic, or icteric specimens may yield unreliable results.
Hemolysis max
100
Lipemia max
100
Icterus max
50
TAT
24–72 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms related to vitamin D deficiency, kidney disease, or conditions affecting hormone transport. It may also be part of a broader evaluation for metabolic or endocrine disorders.

What to Expect Before the Test

No special preparation is usually needed. You may fast for 8–12 hours before the test if instructed, but always follow your provider’s specific instructions. Bring any medications you’re currently taking.

What the Test Involves

A healthcare professional will draw blood from a vein in your arm. The sample is sent to a lab for analysis using a specialized immunoassay method to measure DBP concentration.

What the Results Mean

Results help assess how well your body is processing vitamin D and other hormones. Abnormal levels may indicate conditions like kidney disease, liver disorders, or genetic metabolic issues.

Reference range

Titer < 1:10 (Negative); Titer >= 1:10 indicates presumptive evidence of recent or current Chikungunya virus infection. Seroconversion or fourfold rise in titer between acute and convalescent samples confirms recent infection.N/A

Specimen: serum

No special patient preparation required. Samples should ideally be collected at least 5-7 days after onset of symptoms for optimal IgM antibody detection. Acute and convalescent specimens (2-4 weeks apart) are recommended for seroconversion documentation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Vitamin D binding protein levels can provide insight into systemic hormone function, particularly in patients with suspected vitamin D disorders, kidney disease, or endocrine imbalances. Elevated or low levels may guide treatment adjustments or further testing for underlying conditions.

Short name

DBP (Serum)

Frequently asked questions

What causes abnormal vitamin D binding protein levels?
Abnormal levels may result from kidney disease, liver dysfunction, genetic disorders (e.g., familial chylomicron retention disease), or certain medications that affect protein synthesis or hormone transport.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on your lab’s processing time. Your provider will contact you once they are ready to discuss the findings.
Can lifestyle changes affect this test?
While vitamin D binding protein itself isn’t directly influenced by lifestyle, conditions like obesity or certain dietary habits may indirectly impact hormone metabolism. Always follow your provider’s advice regarding test timing and preparation.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy