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Chlamydia Antibody, Serum (Qualitative Fluorescence Immunoassay)

Published: August 9, 2026Updated: August 16, 2026

This test detects antibodies to *Chlamydia trachomatis*, a common bacterial infection that can affect the reproductive system, eyes, or respiratory tract. It helps identify past or current infections.

Quick summary

["This screening test checks for signs of chlamydia infection by detecting your immune system’s response to the bacteria."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
45011-4
Short code
CHLCSF
Synonyms
Chlamydia Ab CSF IA-aCnc
Category
chemistry
Sample
csf
Container
Sterile CSF collection tubes (tube 1 for chemistry/serology), screw-cap cryovial for transport
Units
N/A
Ref low
1
Ref high
2
Fasting
false
Population
adult
Sex
all
Age range
≥ 0 years
Method
Immunoassay (Enzyme Immunoassay/EIA or Chemiluminescent Immunoassay/CLIA)
CPT
86631
SNOMED
313330009
Specimen volume
0.5-1.0 mL of CSF
Stability
Room temperature: 2 hours; Refrigerated (2-8°C): 24 hours; Frozen (-20°C or below): 30 days. Avoid repeated freeze-thaw cycles.
Hemolysis max
200
TAT
24–72 hours
Order
routine

Why This Test Is Done

Doctors may order this test if you have symptoms like unusual discharge, pain during urination, or pelvic pain. It’s also recommended as part of routine screening for sexually active individuals, especially those with multiple partners or new partners. Some healthcare providers may also suggest it for asymptomatic partners of someone diagnosed with chlamydia.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample from a vein in your arm. The test is usually done in a lab setting and may take a few minutes. If you’re pregnant, discuss this test with your provider, as it’s generally safe.

What the Test Results Mean

A positive result means your body has produced antibodies against chlamydia, suggesting past or current infection. A negative result means no detectable antibodies were found at this time. Follow-up testing or treatment may be recommended based on your symptoms and test results.

Possible Side Effects

There are rarely side effects from a blood draw, but you might feel slight discomfort, bruising, or swelling at the injection site. If you experience excessive bleeding, pain, or signs of infection (like fever or redness), contact your healthcare provider.

Reference range

Negative: Antibody not detected. Equivocal: Borderline result, repeat testing recommended in 1-2 weeks. Positive: Antibody detected, suggestive of current or past Chlamydia species infection of the central nervous system.N/A

Specimen: csf

No special patient preparation required. Inform patient of lumbar puncture procedure risks including headache, bleeding, and infection. Obtain informed consent prior to CSF collection.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Chlamydia Antibody Screen (FIA)

Frequently asked questions

What does a positive result indicate?
A positive result suggests you may have been infected with *Chlamydia trachomatis* at some point. This can lead to complications like pelvic inflammatory disease (PID), infertility, or chronic pelvic pain if untreated. Early treatment with antibiotics can prevent these issues.
How often should I get this test?
The frequency depends on your risk factors. If you’re sexually active, especially with multiple partners or new partners, discuss a testing schedule with your healthcare provider. Typically, annual screening is recommended for sexually active individuals under 25 or those with higher risk behaviors.
Can I get this test at home?
No, this test requires a blood sample collected by a healthcare professional in a clinical setting. Home-based tests for chlamydia typically involve urine or vaginal swab samples, not blood.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy